Severity: Warning
Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 143
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 143
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
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Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
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Function: getPubMedXML
File: /var/www/html/application/helpers/my_audit_helper.php
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Function: GetPubMedArticleOutput_2016
File: /var/www/html/application/controllers/Detail.php
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Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
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Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
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Function: require_once
Study Design: Biomechanical study of bovine spines.
Objective: The purpose of this study was to perform a biomechanical test to analyze intervertebral deflections following placement of both 1 and 2 semiconstrained TDRs in the subjacent segments of a long fusion.
Summary Of Background Data: Long-term sequela of long lumbar fusion for scoliosis include adjacent segment disease and flatback syndrome. Total disc replacement (TDR) is a viable option for the treatment of these conditions. Little data has been published regarding the placement of a TDR distal to a scoliosis fusion.
Methods: Six thoracolumbar bovine spines (T12-S1) were instrumented from T12 to L5, with bilateral pedicle screw fixation at each level. L5-L6 and L6-S1 served as the test levels. One TDR (FlexiCore, Stryker Spine, Allendale, NJ) was initially performed adjacent to the fusion, followed by a subsequent TDR insertion at the last spinal segment. The applied load, total specimen deflection, and local transducer deflections were recorded before and after a TDR at both levels. The results were expressed as a percentage of the intact specimen. Flexion, extension, lateral bending, and torsional deflections were recorded.
Results: There were no significant differences (P > 0.05) in sensor deflection observed at the L5-L6 and L6-S1 levels in the anterior and lateral transducers when compared to intact spines specimens. A similar effect was observed at the L5-L6 and L6-S1 levels in the anterior and lateral transducers when compared to intact or prior L5-L6 and intact L6-S1 constructs.
Conclusion: This study has shown that using the FlexiCore system at 1 and/or 2 intervertebral disc spaces caudal to a scoliosis fusion model did not significantly change the sensor deflection at the 2 segments adjacent to a scoliosis fusion construct. Future research will continue to define the clinical setting and patients best suited for management by TDR systems.
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http://dx.doi.org/10.1097/BRS.0b013e3181a8e418 | DOI Listing |
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