[Microbiological diagnosis of chikungunya virus in Spain (2006-2007): case detection in travelers].

Enferm Infecc Microbiol Clin

Servicio de Microbiología Diagnóstica, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, España.

Published: October 2009

Introduction: The chikungunya virus is a clear example of an emergent pathogen, as demonstrated by the important outbreaks reported in recent years on some islands in the Indian Ocean, on the Indian subcontinent, and in Italy. The autochthonous outbreak that took place in Europe has shown that the international health authorities were right in their concern about the possibility that this arbovirus could become established in countries with a temperate climate where the appropriate vectors circulate.

Methods: A total of 308 patients were studied to investigate symptoms consistent with infection by this virus occurring during their stay in, or after their return from, an endemic area. Molecular and/or serological methods were used to seek evidence of infection by chikungunya virus.

Results: Twenty-nine positive cases were diagnosed. The molecular and serological tools are complementary: molecular technology generated positive results at the onset of symptoms and serology provided positive testing in samples with a longer evolution time.

Conclusion: The first cases of infection by chikungunya virus in Spanish travelers have been detected. The tools necessary for correct diagnosis of infection by this virus are available in our country.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.eimc.2008.07.011DOI Listing

Publication Analysis

Top Keywords

chikungunya virus
12
infection virus
8
infection chikungunya
8
virus
5
[microbiological diagnosis
4
chikungunya
4
diagnosis chikungunya
4
virus spain
4
spain 2006-2007
4
2006-2007 case
4

Similar Publications

The clinical profile and outcomes of children with chikungunya infection differ from those observed in adults. As there is a paucity of data on chikungunya infection in children, this study aimed to find the clinical course, complications, and mortality rates of chikungunya infection in children. This was a combined retrospective and prospective observational study.

View Article and Find Full Text PDF

Chikungunya virus (CHIKV) is an arthritogenic alphavirus that has re-emerged to cause large outbreaks of human infections worldwide. There are currently no approved antivirals for treatment of CHIKV infection. Recently, we reported that the ribonucleoside analog 4'-fluorouridine (4'-FlU) is a highly potent inhibitor of CHIKV replication, and targets the viral nsP4 RNA dependent RNA polymerase.

View Article and Find Full Text PDF

The Chikungunya virus (CHIKV) presents substantial public health challenges in the Eastern Mediterranean Region (EMR), with its prevalence and interaction with other arboviruses (ABVs) remaining poorly understood. This systematic review and meta-analysis aimed to assess the prevalence of CHIKV and its association with other ABVs, such as dengue virus (DENV), Rift Valley fever virus (RVFV), malaria, and yellow fever virus (YFV), in the EMR. We systematically searched databases including PubMed, Embase, Web of Science, Scopus, Cochrane Library, CINAHL, PsycINFO, and ScienceDirect to identify epidemiological studies that report CHIKV prevalence and provide odds ratios (ORs) for CHIKV compared to other ABVs.

View Article and Find Full Text PDF

Background: The burden of Aedes aegypti-transmitted viruses such as dengue, chikungunya, and Zika are increasing globally, fueled by urbanization and climate change, with some of the highest current rates of transmission in Asia. Local factors in the built environment have the potential to exacerbate or mitigate transmission.

Methods: In 24 informal urban settlements in Makassar, Indonesia and Suva, Fiji, we tested children under 5 years old for evidence of prior infection with dengue, chikungunya, and Zika viruses by IgG serology.

View Article and Find Full Text PDF

Aedes-borne arboviral human infections in Europe from 2000-2023: a systematic review and meta-analysis.

Travel Med Infect Dis

January 2025

University of Zürich, Epidemiology, Biostatistics and Prevention Institute, Hirschengraben 84, 8001, Zürich, Switzerland; WHO Collaborating Centre for Travellers' Health, Department of Global and Public Health, MilMedBiol Competence Centre, Hirschengraben 84, 8001, Zürich, Switzerland.

Introduction: Aedes-borne arboviral infections, both imported and autochthonous, are reported in Europe. We evaluated the landscape of these infections in Europe over 23 years and attempted to pre-empt the trajectory of impact of these infections in the climatic context of Aedes mosquito expansion in Europe.

Methods: This systematic review was conducted in accordance with PRISMA guidelines and registered in Prospero (CRD42023360259).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!