Children are believed to construct their causal theories through talk and interaction, but with the exception of a few studies, little or nothing is known about how young children justify and build theories of the world together with same-age peers through naturally occurring interaction, Children's sensitivity to when a pair or group of interlocutors who interact frequently together feel that a justification is needed, is an index of developing pragmatic competence (Goetz & Shatz, 1999) and may be influenced by interactive goals and gender identity positioning. Studies suggest that salient contexts for justifications for young children are disagreement and control (e.g. Veneziano & Sinclair, 1995) but researchers have been less recognizant of 'situations in which partners verbally assist in the construction of justifications as a means to maintain contact or create solidarity' (Goetz & Shatz, 1999: 722) as contexts for justifications. The present study examined the spontaneously produced justification constructions in the naturally occurring free play of five friendship groups of preschool-aged children (aged from 3 ; 6 to 5 ; 4), in terms of the motivating context of the justification, marking of the causal relationship with a connective, and causal theories accessed in the talk. Partner expansion (validating justifications) was a salient motivating context for justifications, especially in the talk of friendship groups of girls, and seemed to privilege greater marking of the causal relationship with a connective and less arbitrary reasoning. One group of girls varied their use of validating justifications depending on the theme of play. Results are discussed in terms of the implications of use of validating justifications for children's causal theory building with peers, linguistic development, and pragmatic development.
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http://dx.doi.org/10.1017/S0305000908009069 | DOI Listing |
JHEP Rep
February 2025
Else Kroener Fresenius Center for Digital Health, Medical Faculty Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
Background & Aims: Biliary abnormalities in autoimmune hepatitis (AIH) and interface hepatitis in primary biliary cholangitis (PBC) occur frequently, and misinterpretation may lead to therapeutic mistakes with a negative impact on patients. This study investigates the use of a deep learning (DL)-based pipeline for the diagnosis of AIH and PBC to aid differential diagnosis.
Methods: We conducted a multicenter study across six European referral centers, and built a library of digitized liver biopsy slides dating from 1997 to 2023.
BMC Med Educ
January 2025
Deakin Optometry, School of Medicine, Deakin University, 75 Pigdons Road, Waurn Ponds , VIC, 3216, Australia.
Background: Clinical reasoning is a professional capability required for clinical practice. In preclinical training, clinical reasoning is often taught implicitly, and feedback is focused on discrete outcomes of decision-making. This makes it challenging to provide meaningful feedback on the often-hidden metacognitive process of reasoning to address specific clinical reasoning difficulties.
View Article and Find Full Text PDFPLoS Comput Biol
December 2024
Department of Mathematics, University of Manchester, Manchester, United Kingdom.
Understanding the temporal relationship between key events in an individual's infection history is crucial for disease control. Delay data between events, such as infection and symptom onset times, is doubly censored because the exact time at which these key events occur is generally unknown. Current mathematical models for delay distributions are derived from heuristic justifications.
View Article and Find Full Text PDFJ Clin Epidemiol
December 2024
Edinburgh Clinical Trials Unit, Usher Institute, The University of Edinburgh, Usher Building, 5-7 Little France Road, Edinburgh BioQuarter - Gate 3, Edinburgh EH16 4UX, UK. Electronic address:
Objectives: Stepped wedge cluster randomized trials (SW-CRTs) are an appealing study design because they enable sequential roll out of an intervention across clusters, bringing logistical advantages. This review aimed to evaluate the design rationale, design features, stepped wedge diagram, and analytical approaches of SW-CRTs published in high-impact medical journals from 2020 to 2023, focusing particularly on adherence to key guidelines from the Consolidated Standards of Reporting Trials extension to SW-CRTs.
Study Design And Setting: We conducted searches across PubMed and Cochrane Central Registry of Controlled Trials databases for SW-CRTs published between January 2020 and December 2023 in eight high-impact journals.
Int J Emerg Med
November 2024
Department of Emergency Medicine and Critical Care, CHU Besançon, Besançon, F-25000 , France.
Background: Emergency medical services (EMS) must incorporate the patient's physiologic state and end-of-life wishes when determining whether to initiate and/or continue cardiopulmonary resuscitation (CPR). This study aims to describe and analyze the use of advance directives (ADs) in CPR by emergency physicians (EPs).
Methods: A qualitative approach using semi-directed interviews was conducted.
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