The innermost stable circular orbit (ISCO) of a test particle around a Schwarzschild black hole of mass M has (areal) radius r_{isco}=6MG/c;{2}. If the particle is endowed with mass micro(<
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Foveal hernia: morphological characteristics and result after idiopathic epiretinal membrane peeling.
Arch Soc Esp Oftalmol (Engl Ed)
December 2024
Departamento de Cirugía, Hospital Clínico Universitario de Valencia, Facultad de Medicina, Universidad de Valencia, Valencia, Spain.
Foveal hernia (FH) can be detected by optic coherence tomography. FH refers to the prolapse of the innermost retinal layers into the vitreal cavity. It occurs in patients with an epiretinal membrane that does not cover the central foveal area.
View Article and Find Full Text PDFMultifocal electroretinogram changes after panretinal photocoagulation in early proliferative diabetic retinopathy.
Med Hypothesis Discov Innov Ophthalmol
October 2024
Department of Ophthalmology, Faculty of Medicine, Beni Suef University, Beni Suef, Egypt.
Background: Panretinal photocoagulation (PRP) impacts macular function in eyes with early proliferative diabetic retinopathy (PDR). Herein, we used the multifocal electroretinogram (mfERG) to objectively investigate this concept.
Methods: In this prospective interventional case series, we enrolled patients with treatment-naive early PDR, absence of clinically significant macular edema, and requirement for PRP.
Oriental covalent immobilization of N-glycan binding protein via N-terminal selective modification.
Anal Chim Acta
November 2024
Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China. Electronic address:
Lectin affinity chromatography is one of powerful tools for the study of protein glycosylation. Different lectin proteins can recognize different structures of monosaccharides or oligosaccharide units, allowing for the selective separation of glycopeptides or glycoproteins containing different polysaccharide structures. However, the N-glycans were only partially captured by most of common lectins, reducing the coverage rate of identifying N-glycoconjugates.
View Article and Find Full Text PDFHigh-Throughput Mass Spectrometry Analysis of -Glycans and Protein Markers after Knockdown in the Syngeneic SW480/SW620 Colorectal Cancer Cell Model.
J Proteome Res
April 2024
Nutrition and Food Science Group, Department of Biochemistry, Genetics and Immunology, Faculty of Biology, Universidade de Vigo, Campus Lagoas-Marcosende, 36310 Vigo, Pontevedra (Galicia), Spain.
Disruption of the glycosylation machinery is a common feature in many types of cancer, and colorectal cancer (CRC) is no exception. Core fucosylation is mediated by the enzyme fucosyltransferase 8 (FucT-8), which catalyzes the addition of α1,6-l-fucose to the innermost GlcNAc residue of -glycans. We and others have documented the involvement of FucT-8 and core-fucosylated proteins in CRC progression, in which we addressed core fucosylation in the syngeneic CRC model formed by SW480 and SW620 tumor cell lines from the perspective of alterations in their -glycosylation profile and protein expression as an effect of the knockdown of the gene that encodes FucT-8.
View Article and Find Full Text PDFLight dependent differentiation of outdoors developed purple eggplant (Solanum melongena L.) pericarp layers: Leaf chlorenchyma characteristics of the pericarp layers dissected in the dark.
Plant Physiol Biochem
February 2024
Department of Plant Anatomy, ELTE Eötvös Loránd University Budapest, Pázmány P. S. 1/c, Budapest, H-1117, Hungary. Electronic address:
To interpret the final steps of chlorophyll biosynthesis, detailed knowledge of etiolation symptoms is necessary. Most of our knowledge originates from studies on plant materials grown in complete darkness. Hardly any information is available about the plastid development in internal parenchyma cells of fleshy fruits in which the food supply is almost unlimited.
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