Liposomes in capillary electromigration techniques.

Electrophoresis

Laboratory of Analytical Chemistry, Department of Chemistry, University of Helsinki, Finland.

Published: June 2009

The use of phospholipid vesicles (liposomes) in EKC and CEC, as well as the use of CE for studying liposomes and lipid-analyte aggregates, are briefly reviewed. The works are presented in the order of appearance. The review describes the most common liposome dispersions used for achieving separation of neutral and charged compounds in liposome EKC. The CEC part is divided into two parts, discriminating between liposomes immobilized on capillaries for hindering analytes from interacting with the fused-silica wall and liposomes immobilized on capillaries for achieving chromatographic phases for separation of compounds. Finally, the use of CE for studying liposomes and lipid-analyte aggregates as analytes is discussed in brief.

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http://dx.doi.org/10.1002/elps.200900061DOI Listing

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