Flea allergy dermatitis, or flea-bite hypersensitivity, is the most common small animal dermatologic condition. In some regions of the world, it is the most commonly seen canine disease. This disease does not exist in locations that are inhospitable to fleas, such as those at elevations above 1500 ft or with low humidity (e.g., the desert).Although there are more than 2000 documented species and subspecies of fleas, the cat flea (Ctenocephalides felis felis) is the species most frequently found infesting dogs, cats, and all caged pets in North America.
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Tunis Med
November 2024
Department of Internal Medicine, Rabta University Hospital Center, Tunisia.
Introduction: Sarcoidosis is a chronic inflammatory disease characterized by non-caseous necrotizing epithelial cell granulomas that can affect any organ. Ear, nose, and throat (ENT) involvement is rare. We report two cases of systemic sarcoidosis with ENT onset.
View Article and Find Full Text PDFParasit Vectors
October 2024
Institute for Parasitology, Centre for Infection Medicine, University of Veterinary Medicine Hannover, Buenteweg 17, 30559, Hanover, Germany.
Background: Rhipicephalus sanguineus sensu lato (s.l.) and Ctenocephalides felis are among the most important year-round ectoparasites of dogs.
View Article and Find Full Text PDFNat Commun
August 2024
Department of Veterinary Pathobiology, University of Missouri, Columbia, MO, USA.
Yersinia pestis, the causative agent of plague, is endemic in certain regions due to a stable transmission cycle between rodents and their associated fleas. In addition, fleas are believed to serve as reservoirs that can occasionally cause enzootic plague cycles and explosive epizootic outbreaks that increase human exposure. However, transmission by fleas is inefficient and associated with a shortened lifespan of the flea and rodent hosts, indicating that there remain significant gaps in our understanding of the vector-animal cycle of Y.
View Article and Find Full Text PDFJ Vet Pharmacol Ther
November 2024
Veterinary Medicine Research and Development, Zoetis, Zaventem, Belgium.
Oclacitinib is a novel Janus kinase (JAK) inhibitor that potently inhibits JAK1-dependent cytokines involved in allergy, inflammation, and pruritus (IL-2, IL-4, IL-6, IL-13, and IL-31). Oclacitinib (Apoquel®, Zoetis Inc, Parsippany, NJ) is approved for the treatment/control of pruritus associated with allergic dermatitis and treatment/control of clinical manifestations of atopic dermatitis in dogs at least 12 months of age. To evaluate the effectiveness of oclacitinib in dogs with flea allergy dermatitis, the JAK1 selective inhibitor was tested in a placebo-controlled, masked, single-dose (0.
View Article and Find Full Text PDFVet Dermatol
October 2024
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, Georgia, USA.
Background: Limited information exists about the correlation between clinical history and positive serum (SAT) and intradermal allergen test (IDAT) results in atopic dogs.
Objectives: To evaluate the correlation between clinical history and SAT/IDAT results in atopic dogs.
Animals: Twenty-nine client-owned dogs with nonseasonal atopic dermatitis with or without seasonal exacerbation were enrolled.
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