Hepatic adenomatosis (HA) is characterized by more than 10 adenomas in the liver, frequently scattered within both lobes. The potential for spontaneous bleeding, rupture, and malignant transformation is known. In HA, tumors show hypervascularization on arterial angiography, computed tomography (CT), and magnetic resonance imaging. We report the case of a 32-year-old woman who presented with a large intraparenchymal and subcapsular hematoma in the liver, and an underlying large adenoma with atypical radiologic characteristics detected with multidetector CT imaging. On follow-up CT examination, a large adenoma was clearly visualized at the site of the previous hematoma.

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Background: Familial adenomatous polyposis (FAP) predisposes individuals to duodenal adenomas. This study describes the histopathological features of endoscopic and surgical specimens from the duodenum, as well as genotype-phenotype associations.

Methods: All known FAP patients were included from the Danish Polyposis Register.

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Hepatic adenomatosis is a rare disease consisting of multiple adenomas in otherwise-normal liver parenchyma. Though the discovery of this entity goes back several years, its diagnosis is still challenging in terms of its definition and pathophysiology. Clinically, patients may be completely asymptomatic and the diagnosis is only made incidentally through imaging tests.

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