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Optimising Asthma Self-Management: Preliminary Validation of an Arabic Version of the Inhaler Technique Questionnaire.
Pharmacy (Basel)
January 2025
Pharmacy, School of Health and Biomedical Sciences, RMIT University, Melbourne, VIC 3083, Australia.
Background: Correct inhaler technique is vital for managing respiratory conditions like asthma. Patients from culturally and linguistically diverse backgrounds are at higher risk of sub-optimal adherence and errors in inhaler technique. This study aimed to validate an Arabic version of the inhaler technique questionnaire for self-assessment of the metered-dose inhaler (MDI) technique by assessing agreement between observed and self-reported techniques among Arabic-speaking individuals with asthma in Australia.
View Article and Find Full Text PDFIntegrating BRCA testing into routine prostate cancer care: a multidisciplinary approach by SIUrO and other Italian Scientific Societies.
BMC Cancer
January 2025
Medical and Translational Oncology, Department of Oncology, Azienda Ospedaliera Santa Maria, Viale Tristano Di Joannuccio 1, Terni, 05100, Italy.
Prostate cancer (PCa) ranks among the most prevalent malignancies in men, with notable associations to Hereditary Breast and Ovarian Cancer Syndrome (HBOC) and Lynch Syndrome, both linked to germline likely pathogenetic variant/pathogenetic variant (LPV/PV) in genes involved in DNA repair. Among these genes, BRCA2 in PCa patients is the most frequently altered. Despite progresses, challenges in BRCA carriers detection persist, with a quarter of PCa cases lacking family history.
View Article and Find Full Text PDFPreliminary effectiveness of social prescription and virtual patient information in increasing tertiary prevention among cancer patients (ESPRIT): protocol for a single-centre, randomised controlled pilot trial.
BMJ Open
January 2025
Department of Epidemiology and Preventive Medicine, Medical Sociology, University of Regensburg, Regensburg, Bavaria, Germany.
Introduction: Tertiary prevention through physical activity and psychosocial support can positively impact patient outcomes, such as physical function and quality of life (QoL). However, more research is required on the effectiveness of strategies designed to increase the uptake of tertiary prevention programmes among cancer patients. Here, we present the protocol for a single-centre, randomised controlled pilot trial testing the preliminary effectiveness of social prescription and virtual patient information in increasing tertiary prevention among cancer patients and support persons (SPs) (ESPRIT "ffectiveness of a ocial escription and virtual patient nformation in increasing ertiary prevention" pilot trial).
View Article and Find Full Text PDFFeasibility of a virtual multimodal prehabilitation intervention for patients with cancer undergoing surgery.
Clin Nutr ESPEN
January 2025
School of Human Nutrition, McGill University, 21111 Lakeshore Rd, Sainte-Anne-de-Bellevue, QC, Canada, H9X 3V9; Department of Anesthesia, McGill University, 1001 Decarie Blvd, Montreal, QC, Canada, H4A 3J1; Department of Surgery, McGill University, 1001 Decarie Blvd, Montreal, QC, Canada, H4A 3J1. Electronic address:
Background And Aims: Current prehabilitation programs are often limited by poor recruitment and attrition rates. Remote delivery of prehabilitation may reduce barriers to participation and maximize program retention. We aimed to assess the feasibility (uptake, retention, fidelity), preliminary effectiveness, and acceptability of delivering a technology-supported prehabilitation program remotely to oncologic surgical candidates.
View Article and Find Full Text PDFQuantifying Crystallinity of Amlodipine Maleate in Amorphous Solid Dispersions Produced by Fluidized Bed Granulation Using PAT Tools.
Eur J Pharm Sci
January 2025
Faculty of Pharmacy, University of Ljubljana, 1000 Ljubljana, Slovenia; KRKA, d. d., 8501 Novo Mesto, Slovenia.
One of the main concerns with formulations containing amorphous solid dispersions (ASDs) is their physical stability. Stability can be compromised if a formulation contains any residual crystallinity of an active pharmaceutical ingredient (API) that could act as seeds for further crystallisation. This study presents four methods for crystalline amlodipine maleate quantification in ASD, which were developed using one Raman and three NIR process analysers.
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