Body weight, ovary and uterus weight, the nature of estral cycles, and hypothalamus dopamine and noradrenaline levels and plasma testosterone levels were studied in female GC rats, bred for increased catatonic reactivity, at different stages of the estral cycle (estrus, proestrus). The outbred Wistar strain served as controls. On the background of decreased body weight, GC females showed impairments to the morphological cyclical changes in the ovaries and uterus, with a reduction in ovary weight in diestrus (p < 0.01) and a smaller estrogen-dependent increase in uterus weight in estrus as compared with Wistar females. On the background of decreases in dopamine and noradrenaline contents in the hypothalamus, GC rats showed higher levels of these monoamines in estrus and lower levels in diestrus. Plasma testosterone levels in female GC rats were higher in diestrus than in estrus and in Wistar rats.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s11055-009-9170-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Assessing initial/early aversion-resistant drinking across male and female alcohol-preferring and non-preferring rats.
Alcohol Clin Exp Res (Hoboken)
December 2024
Addiction Neuroscience, Department of Psychology, Indiana Alcohol Research Center, Indiana University Indianapolis, Indianapolis, Indiana, USA.
Background: One trait of alcohol use disorder (AUD) is continuing to drink despite negative consequences. The current study investigated initial/early aversion-resistant drinking (ARD) across selectively bred alcohol-preferring lines to assess aversion resistance with minimal ethanol history and subsequent ethanol-seeking and drinking profiles. Additionally, ARD was assessed in alcohol-preferring and non-preferring rats using a sucrose reinforcer to determine if ARD may be a genetic risk factor for AUD.
View Article and Find Full Text PDFEndocannabinoid involvement in beneficial effects of caloric restriction in a rodent model of comorbid depression and epilepsy.
Prog Neuropsychopharmacol Biol Psychiatry
December 2024
Department of Psychology, Whitworth University, 300 W Hawthorne Rd, Spokane, WA 99251, USA. Electronic address:
Clinically, patients with depression are at a heightened risk for developing epilepsy, and vice versa, suggesting shared mechanisms for this bidirectional comorbidity. Unfortunately, comorbid depression and epilepsy is associated with worsened quality of life and treatment refractoriness, highlighting the need for novel treatment targets and nonpharmacologic supplements to existing therapies. The present study used the Swim-Low Active rat, a well-validated model of depression and epilepsy comorbidity that was selectively bred based on forced swim test behavior, to assess the safety and efficacy of caloric restriction in treating this comorbidity.
View Article and Find Full Text PDFCocktail vaccine for the management of and .
Front Immunol
December 2024
Entomology Laboratory, Division of Parasitology, Indian Council of Agricultural Research (ICAR)- Indian Veterinary Research Institute (IVRI)-Izatnagar, Bareilly, Uttar Pradesh, India.
Introduction: Globally, ticks rank second only to mosquitoes as vectors of deadly pathogens affecting humans and first in transmitting animal pathogens, presenting a significant challenge to human wellness and sustainability of livestock-based industries. Traditional tick control via chemical acaricides impacts on the environment and has led to the emergence of multi-acaricide-resistant tick populations. Use of immunoprophylactic, along with other components of integrated tick management, holds the potential to mitigate tick infestations in a sustainable manner.
View Article and Find Full Text PDFFemale prediabetic rats are protected from vascular dysfunction: the role of nitroso and sulfide signaling.
Biol Res
November 2024
Centre of Experimental Medicine, Institute of Normal and Pathological Physiology, Slovak Academy of Sciences, Bratislava, Slovakia.
Background: The activity of perivascular adipose tissue (PVAT), a specific deposit of adipose tissue surrounding blood vessels, could contribute to sex differences in vascular tone control, particularly in dyslipidemic disorders; however, the mutual associations remain unclear. This study aimed to evaluate the relationships among sex, PVAT and vascular function in Wistar and hereditary hypertriglyceridemic (HTG) rats. Vasoactive responses of the isolated thoracic aorta with preserved or removed PVAT were compared in adult male and female Wistar and HTG rats, and the roles of nitric oxide (NO), hydrogen sulfide (HS), cyclooxygenase (COX) and inflammatory signaling in vascular function were monitored in females.
View Article and Find Full Text PDFThe impact of social isolation on depression-like behavior in carioca high- and low-conditioned freezing rats.
Soc Neurosci
August 2024
Department of Psychology, Pontifical Catholic University of Rio de Janeiro, Rio de Janeiro, Brazil.
This study investigated the impact of social isolation in Carioca High-Conditioned Freezing (CHF) rats, an animal model of generalized anxiety disorder (GAD). Animals selected for high (CHF), low trait anxiety (Carioca Low-Conditioned Freezing, CLF), and control rats from randomly bred populations (CTL) were housed in groups or kept isolated in their cages for 14 consecutive days. On the fifteenth day, all animals underwent the Forced Swimming Test (FST), where the latency to immobility was assessed as a depressive-like measure.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!