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Theoretical analysis of neuronal network's response under different stimulus.
PLoS One
December 2024
School of Science, Beijing University of Posts and Telecommunications, Beijing, China.
Neuromodulation plays a critical role in the normal physiological functions of organisms. With advancements in science and technology, neuromodulation has expanded into various fields. For instance, in the field of engineering, in vitro-cultured neural networks are utilized to perform closed-loop control for achieving complex functionalities.
View Article and Find Full Text PDFNeural functional rehabilitation: exploring neuromuscular reconstruction technology advancements and challenges.
Neural Regen Res
December 2024
Department of Neural Engineering Center, Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences (CAS), Shenzhen, Guangdong Province, China.
Neural machine interface technology is a pioneering approach that aims to address the complex challenges of neurological dysfunctions and disabilities resulting from conditions such as congenital disorders, traumatic injuries, and neurological diseases. Neural machine interface technology establishes direct connections with the brain or peripheral nervous system to restore impaired motor, sensory, and cognitive functions, significantly improving patients' quality of life. This review analyzes the chronological development and integration of various neural machine interface technologies, including regenerative peripheral nerve interfaces, targeted muscle and sensory reinnervation, agonist-antagonist myoneural interfaces, and brain-machine interfaces.
View Article and Find Full Text PDFRadiofrequency Ablation: Honoring the Pioneers of Modern Therapeutic Innovations.
Cureus
November 2024
Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
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- * The technique has significantly advanced over time, improving in safety and effectiveness thanks to ongoing technological developments and research.
- * RFA's growing understanding and application mean it could treat a broader range of chronic pain issues, ultimately enhancing patients' quality of life.
Spinal manipulative therapy (SMT) has been shown to significantly alleviate pain in patients with lumbar disc herniation (LDH), with its effects closely associated with brain function modulation. This study investigates the neural biomarkers linked to pain relief efficacy following a complete SMT treatment cycle in LDH patients. A total of 59 LDH patients were randomized into two groups: SMT treatment (Group 1, n = 28) and sham treatment (ST) (Group 2, n = 31).
View Article and Find Full Text PDFExosomal MicroRNAs in Alzheimer's Disease: Unveiling Their Role and Pioneering Tools for Diagnosis and Treatment.
J Clin Med
November 2024
Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Alzheimer's disease (AD) is a common neurodegenerative disorder that presents a significant health concern, often leading to substantial cognitive decline among older adults. A prominent feature of AD is progressive dementia, which eventually disrupts daily functioning and the ability to live independently. A major challenge in addressing AD is its prolonged pre-symptomatic phase, which makes early detection difficult.
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