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Assessing the relationship between wrist synovitis and anxiety: a study using clinical statistics and Mendelian randomization analysis.
J Orthop Surg Res
January 2025
Department of Sports Medicine, Wuxi 9th People's Hospital Affiliated to Soochow University, Wuxi, Jiangsu, China.
Background: Wrist synovitis often leads to persistent pain, swelling, and limited mobility, causing significant functional impairment and psychological distress, including anxiety. Although arthroscopic synovectomy can alleviate physical symptoms, whether it also improves anxiety and the causal relationship between synovitis and anxiety remains unclear.
Methods: A prospective study was conducted on 44 patients diagnosed with wrist synovitis who underwent arthroscopic synovectomy.
Alpha-glucosidase inhibitor decreases the risk of colorectal adenoma in the aged with Type 2 diabetes.
Sci Rep
January 2025
Department of Gerontology, Wenzhou Central Hospital, Wenzhou, 325000, Zhejiang, China.
The rapidly aging population is fueling a surge in diabetes, especially Type 2, which heightens colorectal cancer (CRC) risk. Colorectal adenoma, a precursor, compounds this trend. Although alpha-glucosidase inhibitors are effective hypoglycemic drugs working in the GI tract, the link between them and colorectal adenoma formation remains unexplored.
View Article and Find Full Text PDFAdvances in Machine Learning-Aided Thermal Imaging for Early Detection of Diabetic Foot Ulcers: A Review.
Biosensors (Basel)
December 2024
Academy for Engineering and Technology, Yiwu Research Institute, Fudan University, Shanghai 200433, China.
The prevention and early warning of foot ulcers are crucial in diabetic care; however, early microvascular lesions are difficult to detect and often diagnosed at later stages, posing serious health risks. Infrared thermal imaging, as a rapid and non-contact clinical examination technology, can sensitively detect hidden neuropathy and vascular lesions for early intervention. This review provides an informative summary of the background, mechanisms, thermal image datasets, and processing techniques used in thermal imaging for warning of diabetic foot ulcers.
View Article and Find Full Text PDFOrbital and sinus rhabdomyosarcoma with concurrent central retinal artery occlusion: A case report.
World J Clin Oncol
December 2024
Department of Ophthalmology, The Sixth Affiliated Hospital of Jinan University, Dongguan 523000, Guangdong Province, China.
Background: Both rhabdomyosarcoma (RMS) and central retinal artery occlusion (CRAO) are rare medical diseases, and their simultaneous occurrence in the same patient is extraordinarily uncommon. This study presents a comprehensive overview of the clinical manifestations, diagnostic imaging results, and therapeutic interventions of a patient with both conditions.
Case Summary: In this report, we present a 30-year-old male who presented with significant protrusion, pain and vision loss and was diagnosed with RMS in the orbit and sinus with CRAO.
Integration of multi-omics transcriptome-wide analysis for the identification of novel therapeutic drug targets in diabetic retinopathy.
J Transl Med
December 2024
Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue, Guangzhou, 510282, China.
Background: Diabetic retinopathy (DR) is the most important complication of Type 2 Diabetes (T2D) in eyes. Despite its prevalence, the early detection and management of DR continue to pose considerable challenges. Our research aims to elucidate potent drug targets that could facilitate the identification of DR and propel advancements in its therapeutic strategies.
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