Objective: To determine whether an approach that assesses patient capabilities for self-management and then tailors coaching support based on this assessment would be more effective in improving outcomes than the usual disease management approach.
Study Design: A quasi-experimental pre-post design was used, with an intervention group coached with a tailored approach and a control group coached in the usual way.
Methods: Data derived from telephonic coaching and from archival utilization data were used in the analysis. Differences in activation scores, clinical indicators, and utilization rates between intervention and control group members were assessed. Propensity scores were used to weigh the data and equalize baseline differences between the intervention and control groups. Analysis of variance repeated measures were used to examine changes over time. This analytic approach assessed whether individual changes over time in the intervention group were significantly different from individual changes over time in the control group.
Results: Overall, the findings showed a consistent picture that indicated a positive impact of the tailored intervention. Activation scores increased, clinical indicators improved, and utilization rates declined to a greater extent in the intervention group than in the control group.
Conclusion: The findings suggest that tailoring coaching to patients' activation level and using the same metric to track progress improves the outcomes of disease management.
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Ecotoxicol Environ Saf
January 2025
State Key Laboratory of Swine and Poultry Breeding Industry, Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, College of Animal Science and Technology, Sichuan Agricultural University, Chendu 611130, PR China. Electronic address:
Copper is an essential trace element in biological systems, playing a key role in various physiological functions, including redox reactions and energy metabolism. However, an imbalance in copper homeostasis can induce oxidative stress, mitochondrial dysfunction, and inhibition of the ubiquitin-proteasome system, ultimately leading to significant cytotoxicity and cell death. According to recent research, copper can bind to lipoylation sites on proteins involved in the tricarboxylic acid cycle, causing aggregation of lipoylated proteins, the loss of Fe-S cluster proteins, proteotoxic stress, and ultimately, cell death.
View Article and Find Full Text PDFMusculoskelet Sci Pract
January 2025
President & Chief Executive Officer Myopain Seminars, Bethesda, MD, USA; Department of Physical Therapy and Rehabilitation Science, School of Medicine, University of Maryland, Baltimore, MD, USA.
Background: Headache disorders are prevalent often leading to disability. The rectus capitus posterior major muscle (RCPMaj) may contribute to headache symptoms via nociceptive convergence and myodural bridging.
Objectives: To establish guidelines for needle length and needle angle to mitigate risks during dry needling RCPMaj.
Am J Surg
January 2025
Department of Surgery, 1300 York Avenue, Weill Cornell Medicine, New York, NY, 10065, USA.
The benefit of adjuvant radiation therapy (RT) in adrenocortical carcinoma (ACC) is not well characterized for those who undergo initial R0 surgical resection. Patients in the NCDB who underwent R0 resection were placed into two cohorts - those who underwent adjuvant RT and those who did not. 388 patients were identified with 51 receiving RT.
View Article and Find Full Text PDFJ ECT
November 2024
Department of Psychiatry and Health Behavior, Medical College of Georgia at Augusta University, Augusta, GA.
Electroconvulsive therapy (ECT) is underused, logistically challenging for those who are justice-involved, and laced with ethical problems for those on death row. Herein we describe a case of a man without history of long-standing psychiatric illness who, after more than 15 years on death row, was hospitalized for altered mental status. After medical stabilization, the altered mental status persisted.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!