Appropriately substituted nonracemic allyl alcohols, readily prepared from the corresponding enones by application of the CBS methodology, were converted to optically active cycloheptenone derivatives with almost complete transfer of chirality via an efficient "one-pot", cycloisomerization/Claisen rearrangement process. This methodology was directly applied to the expedient total synthesis of (-)-frondosin B.
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http://dx.doi.org/10.1021/ol900967j | DOI Listing |
Front Plant Sci
December 2024
Zhejiang Provincial Key Laboratory of Plant Evolutionary Ecology and Conservation, College of Life Sciences, Taizhou University, Taizhou, China.
var. is a special berry plant of in the Rosaceae family. Its leaves contain high-sweetness, low-calorie, and non-toxic sweet ingredients, known as rubusoside.
View Article and Find Full Text PDFLINE-1 (L1) retrotransposition is widespread in many cancers, especially those with a high burden of chromosomal rearrangements. However, whether and to what degree L1 activity directly impacts genome integrity is unclear. Here, we apply whole-genome sequencing to experimental models of L1 expression to comprehensively define the spectrum of genomic changes caused by L1.
View Article and Find Full Text PDFJ Transl Med
January 2025
Cancer Center, The First Hospital of Jilin University, Changchun, 130021, China.
Ferroptosis and autophagy are two main forms of regulated cell death (RCD). Ferroptosis is a newly identified RCD driven by iron accumulation and lipid peroxidation. Autophagy is a self-degradation system through membrane rearrangement.
View Article and Find Full Text PDFCogn Affect Behav Neurosci
January 2025
Kangbai Hospital, Hangzhou, Zhengjia, China.
The viewpoint that unitization provides a possibility of increasing the contribution of familiarity to associative memory has been widely accepted, but its effects on associative memory and recollection remain controversial. The current study aims to explain these mixed results by considering a potential moderator: changes in the level of unitization from encoding to retrieval phases. During the encoding phase, participants learned the related and unrelated picture pairs (i.
View Article and Find Full Text PDFFood Chem
January 2025
College of Food Science and Engineering, Guiyang University, Guiyang, Guizhou 550005, PR China; Engineering Technology Research Center for Processing and Comprehensive Utilization of Idesia polycarpa, National Forestry and Grassland Administration of the People's Republic of China, Guiyang, Guizhou 550005, PR China. Electronic address:
Idesia polycarpa Maxim (IPM) cake meal, a major by-product of oil extraction, is often discarded in large quantities, resulting in considerable waste. This study explored the extraction of IPM polysaccharides (IPMPs) from cake meal using the innovative ultrasonic-assisted three-phase partitioning (UTPP) method, in comparison with conventional techniques, including acid, medium-temperature alkali, chelating agent, and enzyme extraction methods. The IPMP-UT prepared via UTPP method achieved superior extraction efficiency (10.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!