In this retrospective clinical study, 6 cases of osteosarcoma of the bone have been analyzed. Five patients were with parosteal osteosarcoma and one with periosteal osteosarcoma. The study was performed at the Clinic for Orthopaedic Surgery in Skopje, Macedonia, from 1995 to 2005. This tumor represents 1.5% of all primary bone tumors treated at the Clinic in the 11 year period. The age of the 6 patients (2 female and 4 male) ranged from 8 to 39 years (average 23.8). The history analysis of the patients showed misinterpreted diagnosis in 50% of the cases, with 83.3% rate of local recurrence, 33.3% of metastases and 33.3% of mortality. Follow-up varied from 11 months to 9 years (average 4.5). The clinical and histopathological findings (identical with those reviewed in the literature) confirmed occurrence of two biologically different types of parosteal osteosarcoma: predominant type is originally "benign" but has a definite malignant potential, causing metastases after long symptom-free interval. The other type is highly malignant from the beginning. More radical surgery is recommended for the latter category of tumors, followed by chemotherapy. Compartmental, radical "en bloc" resection, followed by regular review of the patients, is recommended for the former (Tab. 1, Fig. 3, Ref. 20). Full Text (Free, PDF) www.bmj.sk.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Silent surface osteosarcoma treated following the hemi-capanna technique. A case report.
Acta Ortop Mex
November 2024
Equipo, Hospital Clínico San Carlos, Madrid España.
Introduction: surface sarcomas are a rare entity that need correct diagnosis to differentiate parosteal (cPOS), periosteal and the high grade surface osteosarcomas (HGSO). HGSO has malignant behavior similarities with osteosarcomas and wide resection is the key to a successful treatment.1 The Capanna and Hemi-Capanna reconstruction techniques have being developed in order to avoid amputation after an oncological resection, allowing structural support from an allograft and biological advantages from a vascularised autograft.
View Article and Find Full Text PDFDedifferentiated parosteal osteosarcoma with a novel low-grade leiomyosarcomatous and high-grade conventional osteosarcomatous differentiation: Case report and review of literature.
Int J Surg Case Rep
December 2024
Department of Orthopedic, Faculty of Medicine, King Abdulaziz University and King Abdulaziz University Hospital, Jeddah 22252, Saudi Arabia.
Introduction & Importance: Parosteal osteosarcoma is an uncommon, low-grade, well differentiated malignant bone neoplasm with a more favorable prognosis compared to other types of osteosarcoma. Dedifferentiation is a well-known phenomenon, observed in 16-24.6 % of cases, leads to a combination of low-grade fibroblastic osteosarcoma and high-grade sarcoma.
View Article and Find Full Text PDFDiagnostic challenge in chondromyxoid fibroma clinically mimicking neuroma.
Contemp Oncol (Pozn)
October 2024
Department of Pathology, Chair of Oncology, Medical University of Łódź, Łódź, Poland.
Article Synopsis
- Chondromyxoid fibromas (CMF) are rare benign bone tumors that can cause symptoms like pain or swelling, but may also be asymptomatic, making diagnosis difficult.
- This report details a case of a 66-year-old woman whose tumor was initially misdiagnosed as a neuroma, later thought to be a low-grade osteosarcoma after surgery.
- Ultimately, advanced testing confirmed it was a chondromyxoid fibroma, highlighting the need for thorough diagnostic approaches for accurate identification of these tumors.
Osteochondroma-like parosteal osteosarcoma: A case highlighting diagnostic challenge and surgical advances.
Radiol Case Rep
September 2024
Department of Radiology, University of California Davis Medical Center, 4860 Y Street, Suite 3100, Sacramento, CA 95817, USA.
Parosteal osteosarcomas are uncommon malignant bone tumors that arise from the bone surface. Their heterogenous components can present challenges in diagnosis. We present a case of a rare variant of this tumor known as an osteochondroma-like parosteal osteosarcoma, which was initially misdiagnosed as a cartilaginous tumor on core needle biopsy.
View Article and Find Full Text PDFIs still effective massive allograft reconstruction in parosteal osteosarcoma of the distal femur? Review of the literature and advantages of newer technologies.
J Orthop Surg Res
July 2024
Department of Orthopedics and Orthopedic Oncology, University of Padova, Via Giustiniani 3, 35128, Padua, Italy.
Article Synopsis
- Parosteal Osteosarcoma is a low-grade bone cancer typically found in the distal femur of young adults, prompting a review of surgical techniques and reconstruction methods.
- The study evaluated 12 prior studies with 151 patients, noting that most reconstructions involved grafts rather than prosthetics, and reported a low recurrence rate and high functional scores post-surgery.
- The introduction of custom-made 3D-printed cutting guides in surgery improved the ease of the procedure and outcomes, allowing for better surgical precision and faster recovery times.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!