AI Article Synopsis
- Besifloxacin is a new fluoroquinolone antibiotic approved for treating eye infections, and its effectiveness was tested on 2,690 clinical isolates from 40 different species.
- It showed strong potency against gram-positive bacteria and anaerobes, outperforming other tested agents in this regard.
- Additionally, besifloxacin was as effective as other fluoroquinolones against most gram-negative bacteria, including those resistant to other antibiotic classes.
Article Abstract
The antibacterial spectrum of besifloxacin, a novel fluoroquinolone recently approved for treatment of ocular infections, was studied using 2,690 clinical isolates representing 40 species. Overall, besifloxacin was the most potent agent tested against gram-positive pathogens and anaerobes and was generally equivalent to comparator fluoroquinolones in activity against most gram-negative pathogens. Besifloxacin demonstrated potent, broad-spectrum activity, which was particularly notable against gram-positive and gram-negative isolates that were resistant to other fluoroquinolones and classes of antibacterial agents.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715578 | PMC |
| http://dx.doi.org/10.1128/AAC.00418-09 | DOI Listing |
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