Objective: To develop a new method of using existing bronchoscopic video technology to generate a 3D model of the airway for clinical purposes.
Design: Prospective pilot study with clinical correlation.
Methods: A Storz 7200 bronchoscope was used to obtain video of a standardized tube. The images were then processed using "open source" tools which detected feature points. A three dimensional model was then constructed using these feature points. An in-house 3D image program was then used to compare the 3D model with the standardized tube. Video from a representative airway patient who had previously had a CT of the chest and a bronchoscopic examination was also analyzed using this technique. The 3D model was correlated with CT images to clinically validate this technique.
Setting: Tertiary care hospital.
Patients: One airway patient video was used for clinical validation.
Outcome Measures: (1) Average diameters of the 3D video derived tube model were compared to the actual tube and (2) a cross section of the 3D video derived patient model was compared to the patient CT derived model.
Results: Repeated measures on standardized tubes demonstrated that is it possible to construct an airway model using this novel technique with a less than 5% error. Further, it is possible to construct a 3D model from patient video using existing bronchoscopic technology.
Conclusions: It is possible to extract 3D data from a sequence of 2D images. Further, this 3D model can be used for the purposes of management and planning and is quantitatively accurate and reliable. Initial data suggests that these measurements correlate with actual airway size and may provide a better instrument with which to make surgical decisions.
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http://dx.doi.org/10.1016/j.ijporl.2009.05.009 | DOI Listing |
Eur Neuropsychopharmacol
January 2025
Institute of Biomedical Research of Barcelona (IIBB), Spanish National Research Council (CSIC), 08036 Barcelona, Spain; Systems Neuropharmacology Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Catalonia, Spain; Biomedical Research Networking Centre Consortium on Mental Health (CIBERSAM), Instituto de Salud Carlos III, 28029 Madrid, Spain. Electronic address:
Braz J Otorhinolaryngol
January 2025
Ankara Yıldırım Beyazıt University Faculty of Medicine, Department of Otorhinolaryngology, Ankara, Turkey.
Objectives: The aim of this study was to investigate the risk factors that may cause postoperative otomycosis in patients undergoing Chronic Nonsuppurative Otitis Media (CNSOM) surgery.
Methods: In this retrospective study, 409 out of 523 patients met the inclusion criteria. 44 patients diagnosed with otomycosis CNSOM were analyzed.
Curr Top Med Chem
January 2025
Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education & Research (JSS AHER), Mysuru, Karnataka, India.
Background: Several chemical studies described the physiological efficacy of 1,4- dihydropyridines (DHPs). DHPs bind to specific sites on the α1 subunit of L-type calcium channels, where they demonstrate a more pronounced inhibition of Ca2+ influx in vascular smooth muscle compared to myocardial tissue. This selective inhibition is the basis for their preferential vasodilatory action on peripheral and coronary arteries, a characteristic that underlies their therapeutic utility in managing hypertension and angina.
View Article and Find Full Text PDFJ Ultrasound Med
January 2025
State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing, China.
Objectives: The pathogenesis of premature ovarian insufficiency (POI) not only affects the ovarian structure and function but also gives rise to complications such as osteoporosis and dyslipidemia. Although low-intensity pulsed ultrasound (LIPUS) has been proven effective in treating POI, its impact on the associated complications remains unexplored. Therefore, this study aims to investigate the effects of LIPUS irradiation on osteoporosis and dyslipidemia in a mouse model of POI.
View Article and Find Full Text PDFJ Adv Nurs
January 2025
Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu, China.
Aim: To identify the barriers and enablers in the implementation of evidence-based physical activity (PA) programmes for the improvement of health outcomes among pregnant women with gestational diabetes mellitus (GDM), and to develop strategies for implementing this evidence in clinical practice.
Methods: A convergent mixed-methods study was conducted, integrating a descriptive qualitative research design with a cross-sectional survey. In-depth interview was used to collect the views and cognitions about physical activity from medical staff, leaders and pregnant women.
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