In the present study, porous Ti-10Nb-10Zr alloy scaffolds with different porosities were successfully fabricated by a "space-holder" sintering method. By the addition of biocompatible alloying elements the porous TiNbZr scaffolds achieved significantly higher strength than unalloyed Ti scaffolds of the same porosity. In particular, the porous TiNbZr alloy with 59% porosity exhibited an elastic modulus and plateau stress of 5.6 GPa and 137 MPa, respectively. The porous alloys exhibited excellent ductility during compression tests and the deformation mechanism is mainly governed by bending and buckling of the struts. Cell cultures revealed that SaOS2 osteoblast-like cells grew on the surface and inside the pores and showed good spreading. Cell viability for the porous scaffold was three times higher than the solid counterpart. The present study has demonstrated that the porous TiNbZr alloy scaffolds are promising scaffold biomaterials for bone tissue engineering by virtue of their appropriate mechanical properties, highly porous structure and excellent biocompatibility.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.actbio.2009.06.002 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Microstructural, Biomechanical, and In Vitro Studies of Ti-Nb-Zr Alloys Fabricated by Powder Metallurgy.
Materials (Basel)
June 2023
BCAST, Institute of Materials and Manufacturing, Brunel University London, Uxbridge, London UB8 3PH, UK.
This study investigated the microstructures, mechanical performances, corrosion resistances, and in vitro studies of porous Ti-xNb-10Zr (x: 10 and 20; at. %) alloys. The alloys were fabricated by powder metallurgy with two categories of porosities, i.
View Article and Find Full Text PDFBiomedical Ti-Nb-Zr Foams Prepared by Means of Thermal Dealloying Process and Electrochemical Modification.
Materials (Basel)
March 2022
Institute of Materials Science and Engineering, Poznan University of Technology, Jana Pawla II 24, 61-138 Poznan, Poland.
The paper presents results of preparation and modification of Ti20Nb5Zr foams by a thermal dealloying method followed by electrochemical modification. The first step of this study was the preparation of Ti20Nb5Zr30Mg nanopowder using mechanical alloying (MA). The second was forming green compacts by cold pressing and then sintering with magnesium dealloyed from the structure, which resulted in pores formation.
View Article and Find Full Text PDFReplication and bioactivation of Ti-based alloy scaffold macroscopically identical to cancellous bone from polymeric template with TiNbZr powders.
J Mech Behav Biomed Mater
December 2018
Faculty of Materials and Energy, Southwest University, Chongqing 400715, PR China; Chongqing Key Laboratory for Advanced Materials and Technologies of Clean Energy, Southwest University, Chongqing 400715, PR China.
In the present work, a new type of porous Ti-based alloy scaffold with high porosity (about 75%) and interconnected pores in the range of 300-1000 µm was fabricated by polymeric foam replication method with TiNbZr powders. This porous scaffold, which is consisted with major β phase Ti and minor α Ti phase, exhibits a compressive strength of 14.9 MPa and an elastic modulus of 0.
View Article and Find Full Text PDFPhase Stability and Properties of Ti-Nb-Zr Thin Films and Their Dependence on Zr Addition.
Materials (Basel)
August 2018
Department of Energy and Mechanical Engineering and Institute of Marine Industry, Gyeonsang National University, 38, Cheondaegukchi-gil, Tongyeong 53064, Korea.
Ternary Ti-Nb-Zr alloys were prepared by a magnetron sputtering method with porous structures observed in some of them. In bulk, in order to control the porous structure, a space holder (NH₄HCO₃) is used in the sintering method. However, in the present work, we show that the porous structure is also dependent on alloy composition.
View Article and Find Full Text PDFPhase composition, microstructure, and mechanical properties of porous Ti-Nb-Zr alloys prepared by a two-step foaming powder metallurgy method.
J Mech Behav Biomed Mater
June 2014
School of Materials Science and Engineering and Jiangsu Key Laboratory for Advanced Metallic Materials, Southeast University, Nanjing 211189, China.
Porous Ti-Nb-Zr alloys with different porosities from 6.06 to 62.8% are prepared by a two-step foaming powder metallurgy method using TiH2, Nb, and Zr powders together with 0 to 50wt% of NH4HCO3.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!