The activity of natural killers and the capacity of peripheral blood mononuclears for the extracellular killing of Candida cells in patients with different forms of candidiasis has been determined in the radiometric test with the use of targets labeled with 3H-uridine RNAase and in the fungicidal test. On the basis of the data thus obtained the conclusion has been made that in candidiasis changes in the activity of natural killers and fungicidal capacity depend on the severity of the disease and the stage of the process. Linear correlation between the activity of natural killers and fungicidal capacity in candidiasis patients at the stage of exacerbation and in healthy persons is absent.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
What are family caregivers' experiences of coordinating end-of-life care at home? A narrative review.
Palliat Support Care
January 2025
School of Nursing and Midwifery, University of Plymouth, Plymouth, UK.
Objectives: People with life-limiting diseases, who are no longer receiving active or curable treatment, often state their preferred place of care and death as the home. This requires coordinating a multidisciplinary approach, using available health and social care services to synchronize care. Family caregivers are key to enabling home-based end-of-life support; however, the 2 elements that facilitate success - coordination and family caregiver - are not necessarily associated as being intertwined or one and the same.
View Article and Find Full Text PDFPlaying a serious game to increase fertility awareness: perceptions of adolescents, parents and teachers.
Hum Fertil (Camb)
December 2025
Instituto Superior Miguel Torga, Coimbra, Portugal.
Infertility is increasing globally, affecting one in six adults due to factors like delayed childbearing and lifestyle changes. Despite the recognition of the importance of increasing fertility awareness, levels remain low. This study evaluated the perceptions of 'FActs!', a serious game aimed at improving adolescents' fertility awareness.
View Article and Find Full Text PDFSubtilosin A production is influenced by surfactin levels in .
Microlife
January 2025
DTU Bioengineering, Technical University of Denmark, 2800 Kgs Lyngby, Denmark.
Although not essential for their growth, the production of secondary metabolites increases the fitness of the producing microorganisms in their natural habitat by enhancing establishment, competition, and nutrient acquisition. The Gram-positive soil-dwelling bacterium, , produces a variety of secondary metabolites. Here, we investigated the regulatory relationship between the non-ribosomal peptide surfactin and the sactipeptide bacteriocin subtilosin A.
View Article and Find Full Text PDFExamining the impacts of natural and anthropogenic influences on aquatic macrophytes in shallow lakes is crucial for their effective restoration and management. However, there is a lack of direct evidence regarding past species composition or detailed and continuous evidence of recent changes in aquatic macrophyte communities. This study utilized plant macrofossil remains deposited in the sediment, combined with macrophyte surveys from 1983 to 2010, to reconstruct the historical changes in the macrophyte community over approximately 160 years in Lake Weishan, a sub-lake of Lake Nansi located in the lower Yellow River (Huanghe River) Basin, northern China.
View Article and Find Full Text PDFMachine learning and molecular dynamics simulations predict potential TGR5 agonists for type 2 diabetes treatment.
Front Chem
January 2025
African Society for Bioinformatics and Computational Biology, Cape Town, South Africa.
Introduction: Treatment of type 2 diabetes (T2D) remains a significant challenge because of its multifactorial nature and complex metabolic pathways. There is growing interest in finding new therapeutic targets that could lead to safer and more effective treatment options. Takeda G protein-coupled receptor 5 (TGR5) is a promising antidiabetic target that plays a key role in metabolic regulation, especially in glucose homeostasis and energy expenditure.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!