Codeveloping alongside chemistry and in vitro screening, compound management was one of the first areas in research recognizing the need for efficient processes and workflows. Material management groups have centralized, automated, miniaturized and, importantly, found out what not to do with compounds. While driving down cost and improving quality in storage and processing, researchers still face the challenge of interfacing optimally with changing business processes, in screening groups, and with external vendors and focusing on biologicals in many companies. Here we review our strategy to provide a seamless link between compound acquisition and screening operations and the impact of material management on quality of the downstream processes. Although this is driven in part by new technologies and improved quality control within material management, redefining team structures and roles also drives job satisfaction and motivation in our teams with a subsequent positive impact on cycle times and customer feedback.
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http://dx.doi.org/10.1177/1087057109333978 | DOI Listing |
Sensors (Basel)
December 2024
Department of Electrical and Electronic Information Engineering, Toyohashi University of Technology, Toyohashi 441-8580, Japan.
Ethanol (EtOH) gas detection has garnered considerable attention owing to its wide range of applications in industries such as food, pharmaceuticals, medical diagnostics, and fuel management. The development of highly sensitive EtOH-gas sensors has become a focus of research. This study proposes an optical interferometric surface stress sensor for detecting EtOH gas.
View Article and Find Full Text PDFSensors (Basel)
December 2024
Department of Mechanical & Aerospace Engineering, Monash University, Clayton, VIC 3800, Australia.
This study presents a novel approach for monitoring waste substrate digestion under high-density polyethylene (HDPE) geomembranes in sewage treatment plants. The method integrates infrared thermal imaging with a clustering algorithm to predict the distribution of various substrates beneath Traditional outdoor large-scale opaque geomembranes, using solar radiation as an excitation source. The technique leverages ambient weather conditions to assess the thermal responses of HDPE covers.
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December 2024
Innovation Platform of Micro/Nano Technology for Biosensing, ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 311200, China.
As a crucial biomarker for the early warning and prognosis of liver cancer diseases, elevated levels of alpha-fetoprotein (AFP) are associated with hepatocellular carcinoma and germ cell tumors. Herein, we present a novel signal-on electrochemical aptamer sensor, utilizing AuNPs-MXene composite materials, for sensitive AFP quantitation. The AuNPs-MXene composite was synthesized through a simple one-step method and modified on portable microelectrodes.
View Article and Find Full Text PDFPolymers (Basel)
December 2024
Division of Packaging Technology, School of Agro-Industry, Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.
This study investigates the microstructural characterization of cellulose nanocrystals (CNC) and microcellulose (MC) extracted from bamboo fibers () and their potential as reinforcement agents in ordinary Portland cement (OPC) composites. CNC with a mean particle size of 29.3 nm and MC with a mean size of 14.
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December 2024
Department of Technology and Entrepreneurship in Wood Industry, Institute of Wood Sciences and Furniture, Warsaw University of Life Sciences-SGGW, 159 Nowoursynowska St., 02-776 Warsaw, Poland.
This study investigates the properties of composites produced using post-consumer polypropylene (PP) reinforced with lignocellulosic fillers from (black cumin) and rapeseed pomace. Using agri-food by-products like pomace supports waste management efforts and reduces the demand for wood in wood-plastic composites. The composite production method combined extrusion and hot flat pressing.
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