2-(1,1-Dioxo-2H-[1,2,4]benzothiadiazin-3-yl)-1-hydroxynaphthalene derivatives as potential anti-HCV drugs targeting NS5B polymerase have been investigated. Their synthesis, HCV NS5B polymerase inhibition and replicon activity are discussed.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmcl.2009.05.063 | DOI Listing |
Publication Analysis
Top Keywords
ns5b polymerase
12
hcv ns5b
8
2-11-dioxo-2h-[124]benzothiadiazin-3-yl-1-hydroxynaphthalene derivatives
8
polymerase inhibitors
4
inhibitors synthesis
4
synthesis vitro
4
vitro activity
4
activity 2-11-dioxo-2h-[124]benzothiadiazin-3-yl-1-hydroxynaphthalene
4
derivatives 2-11-dioxo-2h-[124]benzothiadiazin-3-yl-1-hydroxynaphthalene
4
derivatives potential
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!