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Dihydropyrimidine enzyme activity and its effect on chemotherapy toxicity: importance of genetic testing.
Cancer Chemother Pharmacol
January 2025
Markey Cancer Center, University of Kentucky, Lexington, KY, USA.
Purpose: Patients with partial or complete DPD deficiency have decreased capacity to degrade fluorouracil and are at risk of developing toxicity, which can be even life-threatening.
Case: A 43-year-old man with moderately differentiated rectal adenocarcinoma on capecitabine presented to the emergency department with complaints of nausea, vomiting, diarrhea, weakness, and lower abdominal pain for several days. Laboratory findings include grade 4 neutropenia (ANC 10) and thrombocytopenia (platelets 36,000).
Undifferentiated pleomorphic sarcoma in the maxillary sinus: a case report.
J Med Case Rep
January 2025
Department of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Background: Undifferentiated pleomorphic sarcoma, previously called malignant fibrous histiocytoma, is a type of malignant mesenchymal tumor (sarcoma) of soft tissue and sometimes bone. It is uncommon in the oral cavity and very sporadic in the maxillary sinus. Microscopic diagnosis of this malignancy in the maxillary sinus can be very challenging, because there is a range of features that may overlap with other benign and malignant tumors.
View Article and Find Full Text PDFOpen surgical treatment of a chronic traumatic arteriovenous fistula in the lower extremity: A case report.
Int J Surg Case Rep
January 2025
Department of Vascular Surgery, The third hospital of mianyang, Sichuan Mental Health Center, Mianyang, Sichuan, China.
Introduction And Importance: A traumatic arteriovenous fistula (TAVF) is a vascular injury where an artery and a vein become abnormally connected. Although endovascular intervention is often the first choice for TAVF, some special cases still require open surgery.
Case Presentation: A 65-year-old man developed a chronic AVF in the lower superficial femoral artery (SFA) one year after a farming accident.
Recurrent relapsing remitting Serratia marcescens infective endocarditis in a former drug-using patient.
Diagn Microbiol Infect Dis
January 2025
Department of Radiology, Bichat Hospital, Assistance Publique-Hôpitaux de Paris, 46 rue Henri Huchard, 75018 Paris, France; INSERM U1148, Paris, France; Paris University, Paris, France. Electronic address:
Unusual course of Serratia marcescens (SM) infectious endocarditis (IE) and literature review (2016-2024; 26 cases). A 44-year-old man, with chronic venous ulcers, presented 21/2 years after a MSSA tricuspid valve IE, a tricuspid and aortic valves SM IE . After 6 weeks of antibiotherapy (meropenem i.
View Article and Find Full Text PDFPeri-Implant Epstein-Barr Virus (+) Mucocutaneous Ulcer in an Immunocompetent Patient: Case Report and Review of the Literature.
Clin Implant Dent Relat Res
February 2025
Department of Stomatology, Research Group GIU21/042, University of the Basque Country/EHU, Leioa, Spain.
Epstein-Barr virus (+) mucocutaneous ulcer (EBVMCU) is an uncommon benign lymphoproliferative lesion that develops in immunocompromised patients. We present a special case of EBVMCU located in the peri-implant mucosa and we review the oral cases published to date. An 88-year-old man with no medical history of interest was attended in the dental clinic due to an ulcerated tumor located in the peri-implant mucosa.
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