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Regional Image Quality Scoring for 2-D Echocardiography Using Deep Learning.

Ultrasound Med Biol

January 2025

Department of Circulation and Medical Imaging, Norwegian University of Science and Technology - NTNU, Trondheim, Norway; Health Research, SINTEF, Trondheim, Norway.

Objective: To develop and compare methods to automatically estimate regional ultrasound image quality for echocardiography separate from view correctness.

Methods: Three methods for estimating image quality were developed: (i) classic pixel-based metric: the generalized contrast-to-noise ratio (gCNR), computed on myocardial segments (region of interest) and left ventricle lumen (background), extracted by a U-Net segmentation model; (ii) local image coherence: the average local coherence as predicted by a U-Net model that predicts image coherence from B-mode ultrasound images at the pixel level; (iii) deep convolutional network: an end-to-end deep-learning model that predicts the quality of each region in the image directly. These methods were evaluated against manual regional quality annotations provided by three experienced cardiologists.

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Hyperbaric oxygen therapy and corticosteroids as combined treatment for acute acoustic trauma.

Eur Arch Otorhinolaryngol

January 2025

Motion Sickness and Human Performance Laboratory, The Israel Naval Medical Institute, IDF Medical Corps, Haifa, Israel.

Purpose: Acute acoustic trauma (AAT) is a sudden sensorineural hearing loss (SNHL) due to exposure to high intensity impulse noise. There are no acceptable treatment guidelines, although several studies showed steroids could be effective in restoring hearing levels. A recent report suggested that steroids combined with hyperbaric oxygen therapy (HBOT) are a superior regiment for AAT.

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The brain faces the challenging task of preserving a consistent portrayal of the external world in the face of disruptive sensory inputs. What alterations occur in sensory representation amidst noise, and how does brain activity adapt to it? Although it has previously been shown that background white noise (WN) decreases responses to salient sounds, a mechanistic understanding of the brain processes responsible for such changes is lacking. We investigated the effect of background WN on neuronal spiking activity, membrane potential, and network oscillations in the mouse central auditory system.

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Purpose: Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have risen exponentially in usage and have been shown to exert neuroprotective and anti-inflammatory effects across multiple organ systems. This study investigates whether GLP-1RAs influence the risk for age-related ocular diseases.

Design: Retrospective cohort study.

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Purpose: To improve the current method for MRI turbulence quantification which is the intravoxel phase dispersion (IVPD) method. Turbulence is commonly characterized by the Reynolds stress tensor (RST) which describes the velocity covariance matrix. A major source for systematic errors in MRI is the sequence's sensitivity to the variance of the derivatives of velocity, such as the acceleration variance, which can lead to a substantial measurement bias.

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