Photo-induced environmental depletion processes of beta-blockers in river waters.

Photochem Photobiol Sci

AstraZeneca Safety Health and Environment, Brixham, Devon, UK.

Published: June 2009

In order to improve the understanding of the fate and behaviour of pharmaceuticals in the environment there is a need to investigate in-stream depletion mechanisms, e.g. phototransformation of active pharmaceutical ingredients (APIs) in natural surface waters. In this study, abiotic and biotic degradation of selected beta-blockers was measured simultaneously in non-sterilised and sterilised river waters and deionised water (DIW) under simulated sunlight (lambda: 295-800 nm) and dark conditions, and at environmentally relevant concentrations, i.e.

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http://dx.doi.org/10.1039/b817890aDOI Listing

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