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High-throughput sequencing: a breakthrough in molecular diagnosis for precision medicine.
Funct Integr Genomics
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Department of Biotechnology, National Institute of Pharmaceutical Education and Research (NIPER)-Raebareli, Lucknow, 226002, India.
High-resolution insights into the nucleotide arrangement within an organism's genome are pivotal for deciphering its genetic composition, function, and evolutionary trajectory. Over the years, nucleic acid sequencing has been instrumental in driving significant advancements in genomics and molecular biology. The advent of high-throughput or next-generation sequencing (NGS) technologies has revolutionized whole genome sequencing, revealing novel and intriguing features of genomes, such as single nucleotide polymorphisms and lethal mutations in both coding and non-coding regions.
View Article and Find Full Text PDFDecentralized worker-centred occupational management in health care: nationwide survey and alpha testing.
Occup Med (Lond)
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Sciense, New York, NY 10013, USA.
Background: Occupational stress among healthcare workers negatively impacts job satisfaction and patient care quality, jeopardizing healthcare system sustainability. Traditional employer-driven approaches often fail to address these challenges comprehensively, leading to persistent gaps in work condition transparency and well-being.
Aims: To elucidate the working conditions of health workers and introduce a worker-centred, technology-based strategy moving beyond traditional practices and entrenched medical culture.
Testing a Web-Based Interactive Comic Tool to Decrease Obesity Risk Among Racial and Ethnic Minority Preadolescents: Randomized Controlled Trial.
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Graduate School of Public Health Policy, City University of New York, New York, NY, United States.
Background: Childhood obesity prevalence remains high, especially in racial and ethnic minority populations with low incomes. This epidemic is attributed to various dietary behaviors, including increased consumption of energy-dense foods and sugary beverages and decreased intake of fruits and vegetables. Interactive, technology-based approaches are emerging as promising tools to support health behavior changes.
View Article and Find Full Text PDFMitigating anthropogenic climate change with aqueous green energy.
Sci Rep
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School of Earth and Ocean Sciences, University of Victoria, PO Box 1700, Victoria, BC, V8W 2Y2, Canada.
Reaching net zero emissions and limiting global warming to 2 °C requires the widespread introduction of technology-based solutions to draw down existing atmospheric levels and future emissions of CO. One such approach is direct air CO capture and storage (DACCS), a readily available, yet energy-intensive process. The combination of DACCS and ocean thermal energy conversion (OTEC) allows for independently powered carbon capture plants to inject concentrated carbon into deep marine sediments where storage is generally safe and permanent.
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