We present an injection form of tissue-engineering construct on the basis of autogenous human chondroblasts for regeneration of the cartilaginous tissue. A material meeting the requirements for the creation of the injection form of an ITC construct (injectable chondrocyte transplantation) was used as the matrix carrier. The developed construct on the basis of autogenous human chondroblasts and homogenized hemostatic gelatin sponge is now at the stage of complex experimental testing.
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http://dx.doi.org/10.1007/s10517-009-0326-4 | DOI Listing |
Cureus
December 2024
Department of Anatomy, A.T. Still University of Health Sciences - Kirksville College of Osteopathic Medicine, Kirksville, USA.
Erythema multiforme major (EMM) is an acute, immune-mediated mucocutaneous disease that rarely affects the genital mucosal surfaces. This study describes a 39-year-old male with this rare disease and unusual presentation. The patient presented to an emergency department with oral lesions, drainage from both eyes, injected sclera, and characteristic targetoid lesions on the face, upper extremities, torso, and plantar surfaces of the feet.
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December 2024
Department of Anesthesiology, University of Tsukuba, Tsukuba, JPN.
Introduction It has been known that progesterone has central effects, as measured by minimum alveolar concentration in various experimental settings. Previously, we showed that progesterone reduces the sevoflurane requirement for the loss of righting reflex (LORR) using male mice. However, the combination of progesterone and isoflurane has not been studied.
View Article and Find Full Text PDFIBRO Neurosci Rep
June 2025
Department of Pharmacy, University of Mountains, P.O. Box 208, Bangangté, Cameroon.
Background And Aim: To date, there is no treatment to prevent the development of temporal lobe epilepsy, the most common form of drug-resistant epilepsy. A recent study revealed the antiepileptic-like effect of the aqueous extract of . Given the potential of this extract, the antiepileptogenic- and learning and memory-facilitating-like effects of the aqueous extract of were assessed using the kainate-induced post- model.
View Article and Find Full Text PDFJ Nanobiotechnology
January 2025
Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, P.R. China.
Background: Osteoarthritis (OA) is a degenerative joint disease with an immense unmet medical need. FGF18 protein is a potential regenerative factor for cartilage repair. However, traditional protein delivery methods have limited efficacy due to the short lifetime and shallow infiltration.
View Article and Find Full Text PDFBMC Musculoskelet Disord
January 2025
Department of Spine Surgery, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, 210003, China.
The aim of this research was to conduct randomized trials assessing the extent of cement diffusion following robot-assisted percutaneous vertebroplasty (R-PVP) for osteoporotic vertebral compression fractures (OVCF). A total of 96 OVCF patients meeting the inclusion criteria and admitted between January 2023 and November 2023 were included in the study. Among them, 48 patients were assigned to the robotic-assisted PVP group (R-PVP group) and 48 patients were assigned to the traditional PVP group (PVP group).
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