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PrEP15-19 Choices: an implementation study protocol of HIV prevention with oral and long-acting injectable cabotegravir PrEP in real-word settings among sexual and gender minority adolescents in Brazil.
BMJ Open
January 2025
Departamento de Medicina Preventiva, Faculdade de Medicina, Universidade de São Paulo, São Paulo, São Paulo, Brazil.
Introduction: Long-acting injectable (LAI) cabotegravir is a promising new method for preventing HIV. Safe and effective long-acting agents for pre-exposure prophylaxis (PrEP) for HIV infection are needed to increase preventive options among sexual and gender minority adolescents.
Methods And Analysis: This is a multisite, prospective implementation study of three PrEP modalities (LAI-PrEP, event-driven (ED) and daily oral), using a mixed-method design with quantitative and qualitative approaches.
Ankyloglossia and breastfeeding self-efficacy in newborns: a birth cohort study.
BMC Oral Health
January 2025
Department of Pediatric Dentistry, School of Dentistry, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.
Background: The impact of ankyloglossia (tongue-tie) on breastfeeding outcomes may be overestimated and surgical treatment in newborns remains a controversial topic. The aim of the present study was to assess and quantify the impact of ankyloglossia in newborns on breastfeeding self-efficacy at 14 days of life.
Methods: A birth cohort study was conducted involving mothers and newborns soon after childbirth at a public hospital in the city of Canoas, southern Brazil.
Prevalence and management of neuropathic injury caused by dental implant insertion in mandible: a systematic review.
J Oral Facial Pain Headache
June 2024
Department of Dentistry, Brazilian Centre for Evidence Based Research, Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil.
To synthesize scientific knowledge regarding the prevalence of neuropathies and nerve injuries caused by dental implant placement in mandible and the available management. Observational and interventional studies evaluating neuropathies occurrence in adults who underwent dental implant surgery were included. Any neuropathy diagnostic was accepted.
View Article and Find Full Text PDFAssociations between sleep bruxism and primary headaches: a descriptive study.
J Oral Facial Pain Headache
December 2024
Brazilian Centre for Evidence Based Research, 88040-900 Florianópolis, SC, Brazil.
To evaluate the association between definitive sleep bruxism and primary headaches and to analyze other variables that may also be associated with definitive sleep bruxism. A descriptive study was carried out with a sample of adults with a medical indication for polysomnography in Florianópolis, Brazil. Data were collected in three phases: questionnaires, physical examinations and polysomnography.
View Article and Find Full Text PDFEnvironmental and human health risk assessment of potentially toxic elements in rehabilitating iron mine lands in the Brazilian Amazon.
J Environ Manage
January 2025
Instituto Tecnológico Vale, Rua Boaventura da Silva, 955, Belém, 66055-090, PA, Brazil. Electronic address:
Waste pile substrates from Fe mining may carry potentially toxic elements (PTE). Rehabilitation efforts must maintain soil vegetation cover effectively, avoiding the dispersion of particulate matter and reducing the risk to the environment and human health. Therefore, this study aims to evaluate the pseudo-total and extractable contents, perform chemical fractionation, and assess the bioaccessibility and risk of PTE in waste piles of Fe mining in the Eastern Amazon.
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