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Safety and efficacy of fecal microbiota transplantation for viral diseases: A systematic review of clinical trials.
PLoS One
October 2024
HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
Article Synopsis
- The systematic review assessed the efficacy and safety of fecal microbiota transplantation (FMT) in treating various viral diseases, using data from multiple research databases up to November 2023.
- Eight studies involving 196 participants highlighted positive outcomes for diseases like HIV, hepatitis B, COVID-19, and cytomegalovirus, including significant improvements in viral clearance and clinical responses.
- Though FMT showed promise and was deemed safe, the authors noted the need for larger and more comprehensive trials due to small sample sizes and variable responses.
Eosinophilic gastroenteritis-induced intestinal obstruction.
Rev Esp Enferm Dig
September 2024
Gastroenterology , First Affiliated Hospital. China Medical University.
A 53-year-old man presented with abdominal pain and distension, accompanied with vomiting, and weight loss. Then he was treated with gastrointestinal decompression and enema, but the symptom of abdominal pain and distension continued with no relief. He had no drug or food allergies.
View Article and Find Full Text PDFA diagnostic dilemma: cytomegalovirus colitis as an uncommon comorbidity in inflammatory bowel disease: a case report.
Virol J
August 2024
Gastroenterology Department, Damascus Hospital, Almujtahed Street, Damascus, Syria.
Background: The role of cytomegalovirus infection as an opportunistic pathogen in exacerbating ulcerative colitis and its response to treatment remain a topic of ongoing debate. Clinicians encounter numerous challenges, including the criteria for differentiating between an acute ulcerative colitis flare and true cytomegalovirus colitis, the diagnostic tests for identifying cytomegalovirus colitis, and determining the appropriate timing for initiating antiviral therapy.
Case Presentation: A 28-year-old Syrian female with a seven-year history of pancolitis presented with worsening bloody diarrhea, abdominal pain, and tenesmus despite ongoing treatment with azathioprine, mesalazine, and prednisolone.
Washed microbiota transplantation combined with biological agents promotes histological remission in refractory severe ulcerative colitis with recurrent intestinal infection: A case report.
Arab J Gastroenterol
November 2024
Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou 510180, China. Electronic address:
Ulcerative colitis (UC) is a chronic non-specific colitis disease. In recent years, fecal microbiota transplantation (FMT), including improved washed microbiota transplantation (WMT), and biological agents have helped improve the prognosis of patients with UC. However, a significant number of patients with moderate to severe UC do not get relief from glucocorticoids, immunosuppressants, and TNF-α antagonists.
View Article and Find Full Text PDFManagement of immune check-point inhibitor-associated colitis in patients with advanced metastatic cancers: A review article.
J Family Med Prim Care
July 2024
Department of Internal Medicine, Creighton University School of Medicine, United States.
Immune check-point inhibitors (ICPi) are immunomodulating agents, which have revolutionized the management of advanced metastatic cancers. Being immunomodulating agents, they are predisposed to causing colitis. This descriptive review article emphasized on the management of ICPi-associated colitis in advanced metastatic cancers.
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