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Scalarane-based sesterterpenoid RCE-protease inhibitors isolated from the Indonesian marine sponge Carteriospongia foliascens. | LitMetric
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Scalarane-based sesterterpenoid RCE-protease inhibitors isolated from the Indonesian marine sponge Carteriospongia foliascens.

David E Williams Irwin Hollander Larry Feldberg Eileen Frommer Robert Mallon Akbar Tahir Rob van Soest Raymond J Andersen

J Nat Prod

Department of Chemistry, University of British Columbia, Vancouver, BC, Canada.

Published: June 2009

Two new 20,24-bishomo-25-norscalaranes, compounds 1 and 2, and two new and two known 20,24-bishomoscalaranes, compounds 3-6, have been isolated from the Indonesian marine sponge Carteriospongia foliascens. The structures of 1-6 were determined by spectroscopic analysis. Compounds 1 and 3-6 inhibit RCE-protease activity.

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 Source
http://dx.doi.org/10.1021/np900042rDOI Listing

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