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Current status and management of peri-implantitis: A systematic review.
Prim Dent J
December 2024
Buket Acar DDS Assistant Professor, University of Hacettepe, Faculty of Dentistry, Department of Periodontology, Ankara, Turkey.
Aim: To systematically review the literature on the surgical and non-surgical methods for managing peri-implantitis.
Materials And Methods: An electronic search for randomised controlled trials published between 2019 and 2023 in the English language was performed with the Medline/PubMed database according to the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The specific search terms were "periimplantitis", "non-surgical treatment", "surgical treatment" and combinations of these terms.
GANT61 surmounts drug resistance of ADR by upregulating lysosome activities and reducing BCL2 expression in HL-60/ADR cells.
Cancer Cell Int
December 2024
Department of Hematology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, Hunan, 410005, China.
Background: Drug resistance remains a significant obstacle to Acute myeloid leukemia (AML) successful treatment, often leading to therapeutic failure. Our previous studies demonstrated that Glioma-associated oncogene-1 (GLI1) reduces chemotherapy sensitivity and promotes cell proliferation in AML cells. GANT61, an inhibitor of GLI1, emerges as a promising candidate in AML treatment.
View Article and Find Full Text PDFSafety of perioperative intravenous different doses of dexamethasone in primary total joint arthroplasty: a retrospective large-scale cohort study.
BMC Musculoskelet Disord
December 2024
Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, #37 Guoxue Road, Chengdu, 610041, People's Republic of China.
Purpose: Perioperative intravenous different doses of dexamethasone (DEX) can realize effective clinical outcomes in total joint arthroplasty (TJA). However, the effect of different DEX doses on readmission rates and postoperative complications remains unclear.
Methods: We retrospectively analyzed patients who underwent primary TJA between December 2012 and October 2020.
Clinical outcome of root canal obturation using different based sealers: a retrospective cohort study.
BMC Oral Health
December 2024
Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Sakarya University, Sakarya, Turkey.
Background: This study aimed to assess and compare the performance of root canal treatment obturated either with calcium silicate-based or epoxy resin-based root canal sealers on retreatment cases with periapical lesions.
Methods: Patients' radiographic data and clinical records were obtained retrospectively from the computerized patient record system. A total of 44 teeth, 28 teeth treated with calcium silicate-based sealer and 16 teeth treated with epoxy resin-based sealer, were included in the study.
Teaching therapy decision-making to medical students: a prospective mixed-methods evaluation of a curricular innovation.
BMC Med Educ
December 2024
Pontificia Universidad Catolica de Chile, Vicuña Mackenna, Macul, Santiago, Chile.
Background: Therapy decision-making (TDM) is an essential medical skill. However, teaching therapeutic reasoning poses significant challenges. We present a comprehensive TDM course for medical students and report on student satisfaction with the educational strategies, their perceived importance of various TDM domains, and their self-efficacy in incorporating these elements into clinical decisions.
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