[Silo filler's syndrome].

Schweiz Med Wochenschr

Schweizerische Unfallversicherungsanstalt (SUVA), Abteilung Arbeitsmedizin.

Published: October 1991

In 1975 an acute febrile bronchopulmonary illness after massive inhalation of fungal spores in silos was described as "pulmonary mycotoxicosis". Subsequently the disorder was referred to as "silo unloader's syndrome" or as a special form of "organic dust toxic syndrome" (ODTS). In this article the three cases of silo unloader's syndrome recognized by the Swiss National Accident Insurance Company (SUVA) between 1978 and 1989 as being an occupational disease are described. Two of the three patients with ODTS were wrongly diagnosed as suffering from allergic alveolitis and a change of occupation was proposed. Therefore, it is important to recognize ODTS in order to avoid unnecessary treatment and a change of occupation. ODTS can be prevented by technical measures such as prevention of mould formation and, in the case of exposure to fungal spores, use of an adequate breathing mask or a powered dust respirator helmet.

Download full-text PDF

Source

Publication Analysis

Top Keywords

fungal spores
8
change occupation
8
[silo filler's
4
filler's syndrome]
4
syndrome] 1975
4
1975 acute
4
acute febrile
4
febrile bronchopulmonary
4
bronchopulmonary illness
4
illness massive
4

Similar Publications

is the etiologic agent of invasive aspergillosis, a life- threatening fungal pneumonia that is initiated by the inhalation of conidia (spores) into the lung. If the conidia are not cleared, they secrete large quantities of hydrolytic enzymes and toxins as they grow, resulting in extensive damage to pulmonary tissue. Stromal fibroblasts are central responders to tissue damage in many organs, but their functional response to pulmonary injury caused by has not been explored.

View Article and Find Full Text PDF

Fungi infect humans when environmental spores are inhaled into the lungs. The lung is a heterogeneous organ. Conducting airways, including bronchi and bronchioles, branch until terminating in the alveolar airspace where gas exchange occurs.

View Article and Find Full Text PDF

The Translation Initiation Factor eIF2Bα Regulates Development, Stress Response, Amylase Production, and Kojic Acid Synthesis in the Fungus Aspergillus oryzae.

Curr Microbiol

January 2025

Engineering Technological Center of Fungus Active Substances of Fujian Province, College of Biological Sciences and Technology, Minnan Normal University, Zhangzhou, 363000, China.

Translation initiation, which involves numerous protein factors and coordinated control steps, represents the most complicated process during eukaryotic translation. However, the roles of eukaryotic translation initiation factor (eIF) in filamentous fungi are not well clarified. In this study, we investigated the function of eIF2Bα in Aspergillus oryzae, an industrially important filamentous fungus.

View Article and Find Full Text PDF
Article Synopsis
  • Fungal contamination in hospital air can impact the health of staff, patients, and caregivers, with a study in Wuhan revealing that factors like temperature, humidity, and seasonal changes significantly influence fungal concentration rather than disease type or personnel density.
  • The analysis showed that airborne fungal particle sizes are normally distributed, with the highest proportions found in specific size ranges, but the median diameter remained below 3.19 μm across different departments in both winter and summer.
  • The findings suggest a need for improved filtration efficiency for specific fungal particle sizes and the use of appropriate antifungal treatments and hygiene practices in hospital air management.
View Article and Find Full Text PDF

The conserved protein DopA is required for growth, drug tolerance and virulence in Aspergillus fumigatus.

World J Microbiol Biotechnol

December 2024

Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.

The majority of Aspergillus fumigatus reproduction occurs asexually, with large numbers of conidiophores producing small hydrophobic conidia dispersed aerially. When healthy hosts inhale conidia, the mucosal cilia and phagocytosis by the innate immune system can remove them. However, in immunocompromised hosts, the conidia are not removed, which allows them to germinate, forming mycelium that invades host tissues and causes disease.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!