Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1365-2516.2009.02023.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A case is reported of management of massive intraoperative blood loss in a male patient with severe hemophilia. Extirpation of hip pseudotumor with one-stage osteosynthesis with an intramedullary joint-pin in a 43 year old male patient was accompanied with 7.5 l blood loss.
View Article and Find Full Text PDFrFVIIa and NN1731 reduce bleeding in hydroxyethyl starch hemodiluted rabbits.
J Trauma
November 2010
Haemostasis Pharmacology, Novo Nordisk AS, Maaloev, Denmark.
Background: Colloid plasma expanders are used to maintain blood pressure and ensure tissue perfusion during hypovolemia, e.g., caused by traumatic bleeding.
View Article and Find Full Text PDFMechanisms of hydroxyethyl starch-induced dilutional coagulopathy.
J Thromb Haemost
July 2009
Department of Anaesthesiology, Centre for Haemophilia and Thrombosis, Aarhus University Hospital, Aarhus, Denmark.
Background: The biochemical mechanisms causing dilutional coagulopathy following infusion of hydroxyethyl starch 130/0.4 (HES) are not known in detail.
Objectives: To give a detailed biochemical description of the mechanism of coagulopathy following 30%in vivo dilution with HES, to present a systematic ex vivo test of various hemostatic agents, and to investigate the hypothesis that acquired fibrinogen deficiency constitutes the most important determinant of the coagulopathy.
Fibrinogen substitution improves whole blood clot firmness after dilution with hydroxyethyl starch in bleeding patients undergoing radical cystectomy: a randomized, placebo-controlled clinical trial.
J Thromb Haemost
May 2009
Department of Anaesthesiology, Center for Haemophilia and Thrombosis, Aarhus, Denmark.
Summary Background: Infusion of artificial colloids such as hydroxyethyl starch (HES) induces coagulopathy to a greater extent than simple dilution. Several studies have suggested that the coagulopathy could be corrected by substitution with a fibrinogen concentrate.
Objectives: The aims of the present prospective, randomized, placebo-controlled trial were to investigate the hemostatic effect of a fibrinogen concentrate after coagulopathy induced by hydroxyethyl starch in patients experiencing sudden excessive bleeding during elective cystectomy.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!