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Factors Associated with Prolonged Mechanical Ventilation in Late Repair of Tetralogy of Fallot.
Pediatr Cardiol
January 2025
Pediatric Intensive Care Department, Wolfson Medical Center, Holon, Israel.
Research establishing factors associated with duration of mechanical ventilation after Tetralogy of Fallot repair, is mainly based on population presenting at early infancy. There are fewer reports regarding repair after infancy, during childhood and preadolescence. To compare two groups of late TOF repair based on post-operative invasive mechanical ventilation duration and explore associations with pre-operative clinical markers of severity of right ventricular outflow tract obstruction.
View Article and Find Full Text PDFHospice Care in the Emergency Department: An Evolving Landscape.
J Palliat Med
January 2025
Palliative Medicine Division, University of Kansas Medical Center, Kansas City, Kansas, USA.
Despite the increasing focus on goal-concordant care in the emergency department (ED), there is limited data about patients who receive a new hospice referral and the care paths of patients on hospice who present there. Describe the characteristics and clinical course of ED patients who receive a new hospice referral and those already receiving hospice care. Retrospective chart review of all adult patients presenting to the ED from January 2021 to July 2023.
View Article and Find Full Text PDFEmerging Immunotherapies for Disease Modification of Type 1 Diabetes.
Drugs
January 2025
Division of Endocrinology, Department of Pediatrics, College of Medicine, University of Florida, 1699 SW 16th Ave, Building A, Gainesville, FL, 32608, USA.
Type 1 diabetes mellitus (T1DM) is characterized by the progressive, autoimmune-mediated destruction of β cells. As such, restoring immunoregulation early in the disease course is sought to retain endogenous insulin production. Nevertheless, in the more than 100 years since the discovery of insulin, treatment of T1DM has focused primarily on hormone replacement and glucose monitoring.
View Article and Find Full Text PDFIntroduction: In recent years, intravitreal injections (IVT) of vascular endothelial growth factor (VEGF) inhibitors have become the standard of care for several macular disorders. Frequently, the therapeutic course requires numerous injections, posing a burden on patients. Non-adherence to treatment may result in reduced visual outcomes, therefore understanding and addressing the underlying causes is imperative.
View Article and Find Full Text PDFComparing Outcomes and Infection Risk in Medical, Surgical, and Trauma Intensive Care Patients with Alcohol Use Disorder.
Surg Infect (Larchmt)
January 2025
Essentia Institute of Rural Health, Duluth, Minnesota, USA.
Alcohol is the most frequently abused drug in the United States, and alcohol use disorder (AUD) is a common comorbidity in intensive care units (ICUs). We performed a retrospective chart review of patients admitted to an ICU between January 2017 and March 2019 at a tertiary hospital serving a large rural population. Patients with diagnoses of AUDs were included.
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