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Debridement and bone graft fusion via the lateral extracavitary approach combined with lateral and posterior screw-rod fixation in the treatment of thoracic spinal tuberculosis: A retrospective study of 38 cases.
Heliyon
December 2024
Department of Orthopedics, The Second Hospital of Lanzhou University, Lanzhou, 730030, China.
Objectives: Thoracic spinal tuberculosis (TB) is still common, and surgical treatment can rapidly relieve pain, correct deformity, reduce bone loss and prevent further damage to neurological function. We have practiced an efficient and safe surgical method.
Methods: From January 2013 to April 2021, 38 patients with thoracic spinal TB were included in our study.
Optical coherence tomography angiography is a valuable tool for evaluating acute ischemic choriocapillaritis. Tuberculosis and syphilis are the main secondary differentials..
View Article and Find Full Text PDFPrognostic nutritional index and naples prognostic score as biomarkers for the prognosis of incisional wound healing after thoracolumbar tuberculosis surgery.
PLoS One
December 2024
Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Objectives: This study aimed to evaluate and compare the clinical predictive value of prognostic nutritional index (PNI) and naples prognostic score (NPS) as biomarkers for the prognosis of incisional wound healing in patients who underwent thoracolumbar tuberculosis surgery through the posterior approach.
Methods: From January 2019 to October 2021, a total of 124 patients with thoracolumbar tuberculosis who underwent posterior approach debridement and internal fixation were included in this study. We retrospectively analyzed the clinical data, including PNI and NPS.
Management of Thoracolumbar Spinal Tuberculosis by Decompression and Posterior Stabilization with Pedicle Screw Fixation.
J Orthop Case Rep
December 2024
Department of Orthopaedic Surgery, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Introduction: Spinal tuberculosis (TB) is a significant health problem. While chemotherapy is the primary treatment, surgery is necessary in some cases. This study investigates the posterior approach for treating thoracolumbar spinal TB with neurological involvement.
View Article and Find Full Text PDFAnalysis of time-to-positivity data in tuberculosis treatment studies: Identifying a new limit of quantification.
Int J Antimicrob Agents
December 2024
UCSF Center for Tuberculosis, University of California, San Francisco, San Francisco, California, USA; Division of Pulmonary and Critical Care Medicine, University of California, San Francisco, California, USA.
Background: The BACTEC Mycobacteria Growth Indicator Tube (MGIT) machine is the standard globally for detecting viable mycobacteria in patients' sputum. Samples are observed for no longer than 42 days, at which point the sample is declared "negative" for tuberculosis (TB). This time to detection of bacterial growth, referred to as time-to-positivity (TTP), is increasingly of interest not solely as a diagnostic tool, but as a continuous biomarker wherein change in TTP can be used for comparing the bactericidal activity of different TB treatments.
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