The quality of life (QL) was assessed in patients with chronic hepatitis B (CHB). Both overall QL and its selected parameters were impaired in patients above 50 years. Also, QL deteriorated with duration of CHB. In patients with active CHB (frequent and prolonged exacerbation, development of complications, low efficiency of drug therapy) and duration of the disease over 5 years, QL impairment was due to serious limitations in almost all spheres and sub-spheres of life under consideration. QL parameters in patients above 50 years were shown to depend on activity of the infectious process. The higher the activity the worse QL was reported by the patients.
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