AI Article Synopsis

  • Oral cancer is a significant health issue in Taiwan, ranking fourth in males and seventh in females, largely due to a high-risk population engaged in smoking and betel nut chewing.
  • About 50% of new cases present at advanced stages (III or IV), leading to poor survival rates, underscoring the importance of early detection and treatment.
  • The article discusses the necessity for improved screening techniques, preventative measures, and follow-up care, while also reviewing existing literature and outlining future research directions in oral cancer.

Article Abstract

Oral cancer is a fatal disease, accounting for the fourth highest incidence of malignancy in males and the seventh in females in Taiwan. The relatively high prevalence of oral cancer in Taiwan is mainly because there is a high-risk group of 2.5 million people with the habit of smoking and betel nut chewing. Unfortunately, 50% of new cases in our medical center who present with TNM stage III or IV lesions have a shorter than 5-year survival after treatment. This highlights the need for: (1) early treatment of fresh oral cancer cases; (2) screening of the high-risk population to detect new lesions; (3) careful follow-up of cases after treatment; and (4) detection of occult early neck nodal adenopathy in surgical cases. It is generally accepted that prevention and screening of oral cancer are equally important to treatment due to its location. In this review article, we describe the nature of oral cancer and highlight the various conventional and novel methods of screening for this disease and ongoing important related research. Related literature is reviewed and future work that needs to be done is detailed.

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http://dx.doi.org/10.1016/s1726-4901(09)70062-0DOI Listing

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