Objective: Determine the rate of hoarseness in children with cleft palate (CP). Understand the relationship between velopharyngeal insufficiency (VPI) and hoarseness in children with CP.
Study Design: Case series with chart review.
Subjects And Methods: Retrospective chart review of 185 patients with CP treated by a Children's Hospital Cleft Team and born between 1991 and 2001.
Results: Of total patients, 54.1 percent were male and 45.9 percent female. All types of CP were represented. The overall rate of hoarseness was 20.0 percent at age 3-4 and 18.4 percent at age 6-7. The presence of VPI did not correlate with the presence of hoarseness or dysphonia. VPI decreased when comparing age 3-4 (58.4%) with age 6-7 (30.2%, P < 0.001), but the hoarseness rates did not change, 20.8 percent at age 3-4 and 19.5 percent at age 6-7 (P = 0.56).
Conclusion: Patients with CP are thought to have increased risk of voice disturbances due to compensatory articulation mechanisms used when a patient has VPI. However, this study of 185 patients with CP showed no relationship between VPI and hoarseness. The overall rate of hoarseness of this population with CP was within the reported range for the normal population of children. These findings suggest that the theory that VPI causes hoarseness due to compensatory speech mechanisms may be incorrect.
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http://dx.doi.org/10.1016/j.otohns.2009.01.036 | DOI Listing |
J Clin Neurosci
January 2025
Department of Medicine, Allama Iqbal Medical College, Pakistan.
Background: Stroke is a leading cause of death/disability, with notable differences in incidence, prevalence, and mortality observed. Despite advancement in stroke research, notable gaps persist in understanding the overall trend and sex-specific disparities in stroke burden over the past three decades, both in the United States of America (USA) and globally.
Aims: This observational-study aims to investigate evolving trends and sex-specific disparities in the incidence, prevalence, and mortality of stroke in the USA and globally from 1990 to 2021.
Background: The aim of this prospective cohort study is to build evidence on transmission dynamics and risk factors for infections in cholera patient households.
Methods: Household contacts of cholera patients were observed for 1-month after the index cholera patient was admitted to a health facility for stool, serum, and water collection in urban Bukavu in South Kivu, Democratic Republic of the Congo. A infection was defined as a bacterial culture positive result during the 1-month surveillance period and/or a four-fold rise in a O1 serological antibody from baseline to the 1-month follow-up.
Public Health Nutr
January 2025
SEANUTS Indonesian Team/Faculty of Medicine, Universitas Indonesia, Depok, Indonesia.
Objective: The South East Asian Nutrition Survey II Indonesia aimed to provide up-to-date data on dietary intake, nutritional and biochemical status of children aged 0·5-12 years in Indonesia 2019-2020.
Design: Multistage cluster sampling, stratified by geographical location.
Setting: Out of forty-six targeted districts in Indonesia, the study only covered twenty-one districts/cities in Java and Sumatera islands, Indonesia due to COVID-19 pandemic.
Diabetes Obes Metab
January 2025
Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Aim: To explore the holistic impact of socioeconomic and mental health inequalities on the global burden of type 2 diabetes.
Materials And Methods: This cross-sectional study used data on the incidence, disability-adjusted life years (DALYs), and mortality of type 2 diabetes as well as DALYs attributable to risk factors during 1990-2021 from the Global Burden of Disease Study 2021. Average annual percent change (AAPC) was applied to assess the temporal trends from 1990 to 2021.
BMC Public Health
January 2025
One Health Lesson Administrative Intern, Addis Ababa, Ethiopia.
Background: According to the World Health Organization (WHO), there were 1.19 million road traffic accident (RTA)-related deaths in 2021, with a significantly higher death rate in developing countries than in developed countries.
Objective: To assess the distribution of causes of death and associated organ injuries in RTA-related fatalities.
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