The Bioethics Council's Report Who Gets Born? elicited considerable public comment with its recommendation regarding the use of preimplantation genetic diagnosis (PGD) for sex selection for social reasons. The Report was based on a process of deliberative consultation, in which determined efforts had been expended to obtain the views of ordinary New Zealanders. Consequently, the manner in which the recommendations, including this particular one on sex selective PGD, were informed by the consultation is of considerable interest. We argue that the Council is unclear about the role that the views of the public should play in its activities. It appears to place great emphasis on involving the public in formulating policy conclusions through deliberative consultation, but some of its recommendations suggest that the views of the public have only been allowed to play a limited role in its reasoning. Unfortunately, the Council's report does not provide sufficient detail of the reasoning underlying these recommendations. We argue that the Council should have adopted a more transparent style of reporting, thereby enabling the public to understand both the scope of their influence on the Council and the reasoning behind the recommendations. This would have allowed the report to be more constructively critiqued, and the controversy attendant on the release of the report to be minimised.
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Am J Surg
February 2025
Department of Surgery, University of Washington, 1959 NE Pacific Street Box 356410, WA, Seattle, USA.
Introduction: The University of Washington Department of Surgery (DoS) Diversity Council created a survey to understand our socio-demographics, identify gaps regarding Diversity, Equity and Inclusion (DEI) initiatives, and support efforts prioritizing DEI.
Methods: An anonymous, voluntary online survey was administered over 5 weeks to DoS members. Quantitative and qualitative analysis were performed using SurveyMonkey and Dedoose, respectively.
EBioMedicine
February 2025
Institute of Medical Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK; Institute for Clinical Research and Systems Medicine, Health and Medical University, Potsdam, Germany.
Background: Maternal smoking and foetal exposure to nicotine and other harmful chemicals in utero remains a serious public health issue with little knowledge about the underlying genetics and consequences of maternal smoking in ageing individuals. Here, we investigated the epidemiology and genomic architecture of maternal smoking in a middle-aged population and compare the results to effects observed in the developing foetus.
Methods: In the current project, we included 351,562 participants from the UK Biobank (UKB) and estimated exposure to maternal smoking status during pregnancy through self-reporting from the UKB participants about the mother's smoking status around their birth.
J Am Coll Cardiol
March 2025
Ciccarone Center for Prevention of Cardiovascular Disease, Johns Hopkins Medicine, Baltimore, Maryland, USA; American Heart Association Tobacco Regulation and Addiction Center, Dallas, Texas, USA. Electronic address:
Background: Cigarette smoking is a strong risk factor for cardiovascular harm.
Objectives: The study sought to explore the detailed relationships between smoking intensity, pack-years, and time since cessation with inflammation, thrombosis, and subclinical atherosclerosis markers of cardiovascular harm.
Methods: We included 182,364 participants (mean age 58.
J Genet Eng Biotechnol
March 2025
Leather Research Institute, Bangladesh Council of Scientific and Industrial Research, Savar, Dhaka 1350, Bangladesh. Electronic address:
Lime and NaS, used in dehairing in the tannery industry, cause the generation of toxic wastes. Ecological security and financial issues demand a look for innovative approaches to leather dehairing free from pollution. The primary goal of this investigation was to explore keratinolytic protease producing bacteria from tannery waste, their genomic evaluation and to assess their possible use in the dehairing process.
View Article and Find Full Text PDFBr J Nutr
March 2025
The Health Research Unit Zimbabwe, Biomedical Research and Training Institute, Harare, Zimbabwe.
Low vitamin D associated with high parathyroid hormone (PTH) is commonly reported in the context of HIV infection. We determined the association between total 25-hydroxyvitamin-D [25(OH)D] and PTH in adolescents living with HIV, in Zambia and Zimbabwe. Adolescents (11-19 years) perinatally-infected with HIV and established on antiretroviral therapy (ART) for ≥6 months were recruited into a cross-sectional study.
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