Objectives: To assess the performance of the Doumas bilirubin reference method.
Design And Methods: Ring trails using pooled patient specimens, a calibrator and human sera enriched with unconjugated bilirubin were analyzed in five laboratories using the Doumas bilirubin reference method.
Results: The coefficient of variation for the linear measurement range between laboratories ranged from 1-3%.
Conclusions: The Doumas bilirubin reference method is robust and reproducible. Bilirubin results using this method may be used in the development of more accurate and reliable calibrators.
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| http://dx.doi.org/10.1016/j.clinbiochem.2009.05.007 | DOI Listing |
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