AI Article Synopsis
- The study investigated copper, iron, and zinc levels in the blood serum of cats infected with Trypanosoma evansi.
- The cats were divided into control and infected groups, with blood samples collected at three intervals to assess metal concentrations and overall health.
- Results showed higher copper and lower iron and zinc levels in infected cats, along with a reduction in red blood cell count, indicating the infection affects serum metal levels and may lead to metabolic issues.
Article Abstract
The aim of this study was to evaluate the concentrations of copper, iron and zinc in blood serum of cats experimentally infected with Trypanosoma evansi. Animals were divided into two groups: control and infected with T. evansi. The animals were infected with 10(8) trypomastigotes each and parasitemia was estimated daily for 56 days by microscopic examination of smears. Hematological and biochemical parameters were evaluated for monitoring of the disease. Serum metal levels were determined in blood samples collected at days 7, 28 and 56 of the experiment. Inductively coupled plasma optical emission spectrometry was used to measure the levels of copper, iron and zinc. Significant differences were observed among groups (P<0.05). Increased levels of copper and decreased iron and zinc levels were observed. A decrease in the number of red blood cells was also observed 7 days after inoculation. Biochemical parameters were not altered. Therefore, the infection by T. evansi might alter the serum metal levels, causing metabolic disturbances in cats.
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| http://dx.doi.org/10.1016/j.exppara.2009.05.007 | DOI Listing |
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