Objective: To study the circulation, distribution, and genomic diversity of HPVs in common warts in Beijing area of China.
Methods: Forty eight patients with pathologically diagnosed common warts were screened for the presence of HPV with HPV type-specific PCR and direct sequencing analysis. The genomic diversity of HPVs prevalent in Chinese patients was analyzed based on LCR.
Results: Forty one (85.5%) samples were positive for HPV DNA, 13 (31.7%)--HPV-57, 12 (29.3%)--HPV-1a, 7 (17%)--HPV-27 and 5(12.2%)--HPV-2a. Four cases were infected with two different HPV types, two (4.9%) with HPV-1a and HPV-27, one (2.4%) with HPV-1 and HPV-57 and one (2.4%) with HPV-27 and HPV-57. In contrast to the prevalence of single strain of novel HPV-57 variant and HPV-1 prototype, two HPV-2 and three HPV-27 novel variants were found to circulate in Beijing.
Conclusion: HPV-1, -2, -27 and -57 are predominantly prevalent in patients with common warts in Beijing.
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http://dx.doi.org/10.1016/S0895-3988(09)60023-4 | DOI Listing |
J Cosmet Dermatol
January 2025
Hospital for Skin Diseases, Shandong First Medical University, Jinan, Shandong Province, China.
J Med Virol
January 2025
Sao Carlos Institute of Physics, University of Sao Paulo, Sao Paulo, Brazil.
Human papillomavirus (HPV) infections rank as the most prevalent sexually transmitted infections globally. The Brazilian Ministry of Health recommends the topical use of 70%-90% trichloroacetic acid (TAA) for treating condyloma acuminata, yet this method suffers from a high recurrence rate of 36% and requires roughly six applications. Topical photodynamic therapy (PDT) has shown effectiveness in targeting subclinical lesions, but it also necessitates multiple sessions for complete lesion clearance.
View Article and Find Full Text PDFInt Med Case Rep J
January 2025
Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin Hospital, Bandung, Indonesia.
Anogenital warts (AGW) including multiple types of human papillomavirus (HPV) are prevalent. In this context, oncogenic HPV infection leads to anogenital cancers and the lesion is more persistent. Several research on AGW therapy with measles, mumps, and rubella (MMR) vaccine injections have been successful without adverse effects.
View Article and Find Full Text PDFRisk Anal
January 2025
Department of Communication, University of Texas at Arlington, Arlington, Texas, USA.
Approximately 80 million US adults-one in four-are infected with the human papillomavirus (HPV), which causes cancers of the cervix in women, cancers of the anus, penis, and throat in men, and genital warts in both sexes. Although HPV vaccinations are safe, effective, easily affordable, and readily available, a substantial percentage of parents resist recommendations to vaccinate their children against HPV. The current study tests the effects of different vaccination advocacy message strategies on attitudes toward HPV vaccination.
View Article and Find Full Text PDFAm J Transl Res
December 2024
Department of Dermatology, Qingpu Branch of Zhongshan Hospital, Fudan University Shanghai, China.
Objective: To analyze the clinical application value of CO laser combined with 5-aminolevulinic acid photodynamic therapy for periungual and plantar warts.
Methods: Data from patients with periungual and plantar warts treated at Qingpu branch of Zhongshan Hospital, Fudan University between August 2022 and January 2024 were retrospectively analyzed. After screening based on inclusion and exclusion criteria, 96 patients were included and categorized into two groups according to their treatment regimens: a combination group (n=50, receiving CO laser therapy and 5-aminolevulinic acid photodynamic therapy) and a control group (n=46, undergoing CO laser treatment alone).
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