Psychiatric and substance use disorders, separately or combined, are frequent in adolescence. Brief, psychometrically sound screening tools are needed to identify those at-risk. The Global Appraisal of Individual Needs-Short Screener (GAIN-SS) is a brief, inexpensive screener that was derived from the well researched full GAIN interview. However, its validity has not been independently investigated based on independent validated screening instruments in an adolescent clinical population. In this project, the internal consistency, validity, and optimal screening cutoff scores were examined in 95 adolescents, most of whom were receiving treatment, and suffered from internalizing (52%; n = 49), externalizing (66%, n = 63), and co-occurring substance use disorders (55%, n = 56). Results indicated adequate internal consistency and overall and subscale construct validity. Receiver operating characteristics (ROC) analyses revealed that the GSS substance use disorder subscale had adequate sensitivity (88%) and specificity (89%). Psychiatric disorder subscales performed less well. The discussion focuses on the strengths and potential weaknesses of use of the GSS and its potential utility in other populations.
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http://dx.doi.org/10.1080/00952990902825421 | DOI Listing |
Alzheimers Dement
December 2024
Georgia State University, Atlanta, GA, USA.
Background: Beginning new Alzheimer's disease (AD) treatments before AD symptoms are prominent would optimize the benefits of these disease slowing treatments. To accomplish this goal, clinicians must identify measures of early disease progression. As a step in doing this, we set out to characterize the relationships between cognitive complaints, wellbeing, cognitive performance, and metacognitive calibration in older adults in order to inform a model of cognition in typical older adults.
View Article and Find Full Text PDFFront Psychol
December 2024
Department of Psychology, Wilfrid Laurier University, Waterloo, ON, Canada.
Introduction: The aim of the current study is to examine the association between life regret and well-being, through a systematic review.
Methods: Four different databases (PsycINFO, Web of Science, ProQuest, Dissertations & Theses Global, and ERIC) were used to source 31 relevant articles, published between 1989 and 2018.
Results: We conclude that experiencing greater life regret is associated with negative effects on various aspects of well-being, such as life satisfaction and depressive symptoms.
BMJ Evid Based Med
January 2025
Center for Global Development, Washington, District of Columbia, USA.
Background: Health technology assessment (HTA) is a valuable tool for informing the efficient allocation of resources in healthcare. However, the resource-intensive nature of HTA can limit its application, especially in low-resource settings. Adapting HTA processes by assessing the available international evidence offers a pragmatic approach to provide evidence for decision-making where resources are constrained.
View Article and Find Full Text PDFSociol Health Illn
January 2025
Department of Global Health and Social Medicine, King's College London, London, UK.
The National Institute for Health and Care Excellence (NICE) was established a quarter of a century ago in 1999 to regulate the cost-effectiveness of pharmaceuticals (and other health technologies) for the NHS. Drawing on medical sociology theories of corporate bias, neoliberalism, pluralism/polycentricity and regulatory capture, the purpose of this article is to examine the applicability of those theories to NICE as a key regulatory agency in the UK health system. Based on approximately 7 years of documentary research, interviews with expert informants and observations of NICE-related meetings, this paper focuses particularly on NICE's relationship with the interests of the pharmaceutical industry compared with other stakeholder interests at the meso-organisational level.
View Article and Find Full Text PDFBreast J
January 2025
HTA Austria-Austrian Institute for Health Technology Assessment (AIHTA) GmbH, Garnisongasse 7/21, Vienna 1090, Austria.
Purpose: Breast cancer is the most common cancer among women globally, with an incidence of approximately two million cases in 2018. Organised age-based breast cancer screening programs were established worldwide to detect breast cancer earlier and to reduce mortality. Currently, there is substantial anticipation regarding risk-adjusted screening programs, considering various risk factors in addition to age.
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