Objective: To investigate the occurrence of complications in US-guided percutaneous biopsy using core (>19G) gauge cutting needle.

Methods: A retrospective analysis of 5366 US-guided thick needle biopsies was conducted to analyze the incidence of complications after biopsy at different positions.

Results: The total incidence of complications was 1.08%, including most frequent hemorrhage, pneumothorax, hemotysis and infection.

Conclusion: Ultrasound-guided automatic biopsy is easy to operate and safe, and strict execution of the procedures can lower the incidence of the complications.

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