The optimal method of management of clinical N0 neck in squamous cell carcinoma of the oral cavity remains controversial. We used decision analysis to determine the current optimal strategy in comparison with observation of the neck and elective neck dissection. A total of 165 previously untreated patients with N0 classification were investigated. Probabilities of each recurrence were calculated and probabilities of being cured in each event were substituted with the 5-year overall survival calculation with Kaplan-Meier method. A sensitivity analysis was performed to determine the optimal threshold for treatment of the N0 neck. The threshold of N0 neck was calculated using the formula with putting the three probabilities of being cured. In this study the threshold was estimated at 44.4%. N0 neck of squamous cell carcinoma of the oral cavity should be observed if the probability of occult metastasis is less than 44.4%. Proper calculation of three probabilities of being cured in each institution will make a decision of the optimal method of clinical N0 neck by using the threshold formula.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.oraloncology.2009.03.013 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Diversity of central nervous system manifestations in Sjogren's Disease: a case-based review.
Rheumatol Int
January 2025
Department of Rheumatology, Clinical Immunology, Geriatrics and Internal Medicine, Medical University of Gdansk, Gdansk, Poland.
Sjogren's disease (SjD) is a chronic and disabling autoimmune disease, predominantly characterized by dryness of the mouth and eyes, resulting from lymphocytic infiltration of exocrine glands. While these are the most prominent symptoms, extra-glandular manifestations are also common. Studies suggest that up to 70% of SjD patients experience neurological symptoms, which interestingly often precede the hallmark dryness.
View Article and Find Full Text PDFPhotobiomodulation of alveolar bone healing in rats with low-level laser and light emitting diode therapy.
Lasers Med Sci
January 2025
Centro Universitário do Estado do Pará, Belém, Brazil.
The present study investigates the potential contribution of Photobiomodulation (PBM) to the regeneration of the bone following the extraction of the first mandibular molar in rats. The study evaluates the efficacy of PBM, using both Low-Level Laser Therapy (LLLT) and Light-Emitting Diode Therapy (LEDT), as promotors of osteoblastic activity and the formation of new bone. Study design, setting, and sample: 45 male Wistar rats were divided randomly into three groups of 15 individuals - (i) control group (left lower molar removed only), (ii) the LLL group (molar removed, followed by LLLT), and (iii) the LED group (molar removed, followed by LEDT).
View Article and Find Full Text PDFSap Anthropometric Landmark: A Morphometric Orientation Point of the Nasal Tip.
J Craniofac Surg
January 2025
Department of Oral and Maxillofacial Surgery, Azerbaijan Medical University, Baku, Azerbaijan.
The aim of the present study is to introduce a new anthropometric landmark (sap), parameter (sap-sap) for measuring a width of nasal tip and 7 new proportion indexes. For determinate data mean with standard deviation, 200 healthy individuals (100 men and 100 women) were included in the study. The authors determined and pointed 9 paired cranio-facial anthropometric landmarks: sap, al, ac, mf, en, ex, zy, ch, go.
View Article and Find Full Text PDFKeep Your Mouth Shut when Pressured?
Ann Am Thorac Soc
January 2025
Icahn School of Medicine at Mount Sinai, New York, New York, United States;
Clinical and Epidemiologic Review of Capnocytophaga Spp. Infections Identified at a Public Health Reference Laboratory-California, 2005-2021.
Zoonoses Public Health
January 2025
Infectious Diseases Branch, Division of Communicable Disease Control, Center for Infectious Diseases, California Department of Public Health, Sacramento, California, USA.
Introduction: Capnocytophaga is a genus of bacteria that are commensal to the oral microbiome of humans and some animals. Some Capnocytophaga species are found in the human oral cavity and rarely cause disease in people; the species found in animals are zoönotic and can be transmitted to people via saliva. This study describes the clinical and epidemiologic features of patients from whom Capnocytophaga spp.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!