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Seize the Day or Let It Slip Away? The Dilemma of Epilepsy Surgery in Older Adults.
Epilepsy Curr
November 2024
Epilepsy Division, Department of Neurology, School of Medicine, University of Virginia, Charlottesville.
Strong winds reduce foraging success in albatrosses.
Curr Biol
December 2024
School of Environmental Sciences, University of Liverpool, Liverpool L3 5DA, UK.
Knowledge of how animals respond to weather and changes in their physical environment is increasingly important, given the higher frequency of extreme weather recorded in recent years and its forecasted increase globally. Even species considered to be highly adapted to extremes of weather, as albatrosses are to strong winds, may be disadvantaged by shifts in those extremes. Tracked albatrosses were shown recently to avoid storms and the strongest associated winds.
View Article and Find Full Text PDFSeize the day: A quality improvement approach to support transition of care and decrease 30-day readmissions for pediatric patients with epilepsy.
J Pediatr Nurs
November 2024
Nicklaus Children's Hospital, 3100 SW 62(nd) Ave, Miami, FL 33155, USA.
Purpose: Elevated rates of 30-day readmission for children with epilepsy were noted at a stand-alone pediatric acute care facility. To address this issue, a standardized pathway was created and implemented in 2017. The main objective was to ensure that patients with epilepsy and their families were adequately prepared for discharge and the transition to home.
View Article and Find Full Text PDFExploring the benefits of in-diet versus repeated oral dosing of saracatinib (AZD0530) in chronic studies: insights into pharmacokinetics and animal welfare.
Front Vet Sci
November 2023
Department of Biomedical Sciences, College of Veterinary Medicine, Iowa State University, Ames, IA, United States.
Saracatinib/AZD0530 (SAR), a Src tyrosine kinase inhibitor, mitigates seizure-induced brain pathology in epilepsy models upon repeated oral dosing. However, repeated dosing is stressful and can be challenging in some seizing animals. To overcome this issue, we have incorporated SAR-in-Diet and compared serum pharmacokinetics (PK) and brain concentrations with conventional repeated oral dosing.
View Article and Find Full Text PDFBioaccumulation of polystyrene microplastics and changes in antioxidant and AChE pattern in a freshwater snail (Filopaludina bengalensis) from river Ganga.
Aquat Toxicol
October 2023
Aquatic Environmental Biotechnology and Nanotechnology Division, ICAR-Central Inland Fisheries Research Institute, Barrackpore, Kolkata 700120, India. Electronic address:
Microplastic pollution is a leading global problem affecting terrestrial and marine aquatic ecosystems. Due to the stagnant nature of microplastics, the toxic effect of microplastics is more pronounced to benthic organisms than the surface feeder. Hence, the present study effort was to study the microplastic bioaccumulation pattern and changes in the enzymatic and nonenzymatic antioxidant and AChE pattern of freshwater snail Filopaludina bengalensis, which were subjected to 0.
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