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The impact of adult neurogenesis on affective functions: of mice and men.
Mol Psychiatry
August 2024
Institut Pasteur, Université Paris Cité, CNRS UMR 3571, Perception and Action Unit, F-75015, Paris, France.
In most mammals, new neurons are not only produced during embryogenesis but also after birth. Soon after adult neurogenesis was discovered, the influence of recruiting new neurons on cognitive functions, especially on memory, was documented. Likewise, the late process of neuronal production also contributes to affective functions, but this outcome was recognized with more difficulty.
View Article and Find Full Text PDFGranulocytic Sarcoma Mimicking Cholesteatoma: Beware the Temporal Bone in Haematological Patients.
ORL J Otorhinolaryngol Relat Spec
October 2023
Division of Hematology, General Hospital of La Palma, La Palma, Spain.
Granulocytic sarcoma is a myeloid neoplasm that can occur in isolation or in association with acute leukaemia. The temporal bone represents a sanctuary site for myeloid progenitors: granulocytic sarcoma may develop in this location before or concomitantly with the onset of acute leukaemia. This atypical presentation with clinical and radiological data that closely mimic those of cholesteatoma often delays an accurate diagnosis.
View Article and Find Full Text PDFBeware the Grizzlyman: A comparison of job- and industry-based noise exposure estimates using manual coding and the NIOSH NIOCCS machine learning algorithm.
J Occup Environ Hyg
July 2022
Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, Michigan.
Article Synopsis
- The NIOSH updated its coding system (NIOCCS) that uses machine learning to assign codes to industries and jobs based on free-text inputs, but it hasn't been tested for quality with varied input types.
- This study tested NIOCCS's robustness by analyzing over 700,000 noise measurements, comparing different levels of input refinement, and assessing how that affected job-exposure estimates for noise.
- Results showed that less refined inputs led to higher misclassification rates, with refined titles producing more accurate noise exposure estimates, indicating that the quality of input data is crucial for effective machine learning classification.
Beware of covert enemies: malignant otitis externa with base of the skull osteomyelitis, a case report and review of literature.
IDCases
May 2021
Department of Infectious Diseases, Communicable Diseases Centre, Hamad Medical Corporation, Qatar.
Background: Malignant otitis externa (MOE) is a serious infection of the external auditory canal that is frequently associated with skull base osteomyelitis (SBO) as well as secondary neurological sequelae. Patients with poorly controlled diabetes mellitus or immunosuppression are at increased risk of developing such critical infection for multiple local and systemic factors. While most cases are secondary to bacterial infections particularly, fungal infections are also occasionally encountered, often associated with delayed diagnosis and high morbidity and mortality.
View Article and Find Full Text PDFBuyer Beware?: Commentary on an article by Philip-C. Nolte, MD, MA, et al.: "Risk Factors for Revision Surgery Following Radial Head Arthroplasty without Cement for Unreconstructible Radial Head Fractures. Minimum 3-Year Follow-up".
J Bone Joint Surg Am
April 2021
Department of Orthopaedic Surgery, Washington University in St. Louis, St. Louis, Missouri.
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