Identification of a polyketide synthase coding sequence specific for anatoxin-a-producing Oscillatoria cyanobacteria.

Appl Environ Microbiol

Unité des Cyanobactéries (URA CNRS 2172), Institut Pasteur, 28 Rue du Docteur Roux, 75724 Paris Cedex 15, France.

Published: July 2009

We report the identification of a sequence from the genome of Oscillatoria sp. strain PCC 6506 coding for a polyketide synthase. Using 50 axenic cyanobacteria, we found this sequence only in the genomes of Oscillatoria strains producing anatoxin-a or homoanatoxin-a, indicating its likely involvement in the biosynthesis of these toxins.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708435PMC
http://dx.doi.org/10.1128/AEM.02478-08DOI Listing

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