Two-stimuli manipulation of a biological motor.

J Nanobiotechnology

Department of Molecular Cell Biology, VU University Amsterdam, Amsterdam, the Netherlands.

Published: May 2009

AI Article Synopsis

  • F1-ATPase serves as a rotary nano-motor enzyme, with its subunits rotating during the catalytic process.
  • Combining two specific input stimuli can halt the rotation of this motor, while each stimulus alone has little effect.
  • These results could lead to advancements in creating logic gates based on single biological motor molecules.

Article Abstract

F1-ATPase is an enzyme acting as a rotary nano-motor. During catalysis subunits of this enzyme complex rotate relative to other parts of the enzyme. Here we demonstrate that the combination of two input stimuli causes stop of motor rotation. Application of either individual stimulus did not significantly influence motor motion. These findings may contribute to the development of logic gates using single biological motor molecules.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693425PMC
http://dx.doi.org/10.1186/1477-3155-7-3DOI Listing

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