[Studies on triterpenoid saponins in Hemsleya chensnsis].

Zhongguo Zhong Yao Za Zhi

Department of Pharmacology, Wenzhou Medical College, Key Laboratory of Special Traditional Chinese Medicines of Zhejiang Province, Wenzhou 325035, China.

Published: February 2009

Objective: To study the triterpenoid saponins in Hemsleya chensnsis.

Method: The chemical constituents were isolated and purified by various chromatographic methods and their structures were elucidated on the basis of spectral analysis.

Result: Seven known triterpenoid saponins were isolated from the root of H. chensnsis and were identified as 3-O-beta-D-glucuropyranosyl-oleanol-icacid (1), 3-O-beta-D-glucopyra-noside-oleanolicacid-28-O-beta-D-glucopyranoside (2), 3-O-(6'-methylester)-beta-D-glucuropyranosyl olea- nolic acid-28-O-alpha-L-arabinopyranoside (3), 3-O-(6'-methylester)-beta-D- glucuropyranosyl- oleanolic acid-28-O-beta-D-mannupyranoside (4), 3-O-(6'-ethyl ester)-beta-D-glucuropyranosyl oleanolic acid-28-O-beta-D- glucopyranoside (5), 3-O-alpha-L-arabinopyranoside-(1-->3) -beta-D-glucuropyranosyl- oleanolic acid-28-O-beta-D-glucopyranoside (6), 3-O-beta-D-glucu-ropyranosyl-oleanolic acid-28-O-beta-D-glucopyra-noside-(1-->6)-beta-D-glucopyranoside (7).

Conclusion: Compounds 1-7 were isolated from this plant for the first time.

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