Biodegradable poly(ethylene oxide) nanofibers containing silver nanoparticles were successfully prepared by the electrospinning without the further reduction process which could cause the damages of nanofibers. Transmission electron microscopy showed that the silver nanoparticles were dispersed in poly(ethylene oxide) nanofibers without aggregation. This facile process would be the effective method to prepare the silver nanoparticles/polymer nanocomposites. Moreover, the silver nanoparticles embedded in the poly(ethylene oxide) nanofibers were responsible for the antibacterial activities against Staphylococcus aureus and Klebsiella pneumoniae, respectively. Therefore, it is expected that the silver nanoparticles/poly(ethylene oxide) nanocomposites can be used for practical applications as the biomaterial.
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http://dx.doi.org/10.1166/jnn.2009.c096 | DOI Listing |
J Nanobiotechnology
January 2025
Department of Orthopedics, Huashan Hospital, Fudan University, No. 12, Middle Wulumuqi Road, Jing'an District, Shanghai, 200040, China.
Background: Spinal cord injury (SCI) treatment remains a formidable challenge, as current therapeutic approaches provide only marginal relief and fail to reverse the underlying tissue damage. This study aims to develop a novel composite material combining enzymatic nanoparticles and nerve growth factor (NGF) to modulate the immune microenvironment and enhance SCI repair.
Methods: CeMn nanoparticles (NP) and CeMn NP-polyethylene glycol (PEG) nanozymes were synthesized via sol-gel reaction and DSPE-mPEG modification.
BMC Oral Health
January 2025
Department of Oral and Maxillofacial Surgery, Ordu University, Cumhuriyet Yerleşkesi Cumhuriyet Mahallesi, 52200, Ordu, Türkiye, Turkey.
Background: This study evaluates the efficacy of carbon fiber reinforced Polyetheretherketone (Cfr-PEEK) in fixation after sagittal split ramus osteotomy (SSRO) by comparing it with titanium in vitro.
Methods: Twenty-eight sheep hemimandibles were randomly assigned to four groups for SSRO surgery. Fixation was performed with a 4-hole titanium mini plate for 5 mm advancement in Group 1, with a 4-hole Cfr-PEEK mini plate for 5 mm advancement for Group 2, with a 4-hole titanium mini plate for 10 mm advancement for Group 3, and with a 4-hole Cfr-PEEK mini plate for 10 mm advancement for Group 4.
Sci Rep
January 2025
Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, 060-0812, Japan.
Human leukocyte antigen (HLA)-G is a nonclassical HLA class I molecule that has an immunosuppressive effect mediated by binding to immune inhibitory leukocyte immunoglobulin-like receptors (LILR) B1 and LILRB2. A conventional HLA-G isoform, HLA-G1, forms a heterotrimeric complex composed of a heavy chain (α1-α3 domains), β2-microglobulin (β2m) and a cognate peptide. One of the other isoforms, HLA-G2, lacks a α2 domain or β2m to form a nondisulfide-linked homodimer, and its ectodomain specifically binds to LILRB2 expressed in human monocytes, macrophages, and dendritic cells.
View Article and Find Full Text PDFNat Commun
January 2025
State Key Lab of Metal Matrix Composites School of Materials Science and Engineering Shanghai Jiao Tong University 800 Dongchuan Road, Shanghai, P. R. China.
Reactive oxygen species with evoked immunotherapy holds tremendous promise for cancer treatment but has limitations due to its dependence on exogenous excitation and/or endogenous HO and O. Here we report a versatile oxidizing pentavalent bismuth(V) nanoplatform (NaBiO-PEG) can generate reactive oxygen species in an excitation-free and HO- and O-independent manner. Upon exposure to the tumor microenvironment, NaBiO-PEG undergoes continuous H-accelerated hydrolysis with •OH and O generation through electron transfer-mediated Bi-to-Bi conversion and lattice oxygen transformation.
View Article and Find Full Text PDFMedicine (Baltimore)
January 2025
Department of Otorhinolaryngology, Eshisehir Osmangazi University, Eskisehir, Türkiye.
Background: Percutaneous sclerotherapy as endovascular treatment may cause severe complications beside the target area. Pulmonary embolism and thrombosis may occur. In this regard, our study aimed to reveal whether increasing systemic doses of polidocanol affects the coronary or pulmonary alveolar levels.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!