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Ampullary composite gangliocytoma/neuroma and neuroendocrine tumor management.
Endocr Relat Cancer
January 2025
S Gaujoux, Surgery, Hospital Cochin, Paris, 75013, France.
Ampullary composite gangliocytoma/neuroma and neuroendocrine tumor (CoGNET), previously called ampullary gangliocytic paragangliomas (GP) are a rare entity, with only few reported cases in the literature. This is a multicentric retrospective cohort of patients treated with endoscopy or surgery for ampullary CoGNET. A literature review of ampullary CoGNET was also performed.
View Article and Find Full Text PDFPushing the Boundaries of Ampullectomy for Benign Ampullary Tumors: 25-Year Outcomes of Surgical Ampullary Resection Associated with Duodenectomy or Biliary Resection.
J Clin Med
November 2024
Digestive and General Surgery Department, Bellvitge University Hospital, L'Hospitalet de Llobregat, 08907 Barcelona, Spain.
Surgical resection for ampullary lesions lacks clear guidelines. Pancreaticoduodenectomy (PD) is the standard treatment for malignant ampullary tumors but is often excessive for ampullary adenomas (AAs) due to its high morbidity and mortality. Transduodenal ampullectomy (TDA) is generally reserved for small benign lesions where endoscopic treatment fails, but its role in early ampullary cancers is debatable.
View Article and Find Full Text PDFEndoscopic Resection of Post-Transduodenal Ampullectomy Recurrent Ampullary Adenoma Using Clip-with-Line Traction Method (with video).
Gastrointest Endosc
December 2024
Division of Gastroenterology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan; Department of Post-Baccalaureate, Medicine College of Medicine, National Chung Hsing University, Taichung, Taiwan. Electronic address:
Endoscopic papillectomy versus surgical ampullectomy for adenomas and early cancers of the papilla: a retrospective Pancreas2000/European Pancreatic Club analysis.
Gut
December 2024
Department of Digestive and HBP Surgery, Groupe Hospitalier Pitié-Salpêtrière, Médecine Sorbonne Université APHP, Paris, France.
Objective: Ampullary neoplastic lesions can be resected by endoscopic papillectomy (EP) or transduodenal surgical ampullectomy (TSA) while pancreaticoduodenectomy is reserved for more advanced lesions. We present the largest retrospective comparative study analysing EP and TSA.
Design: Of all patients in the database, lesions with prior interventions, benign histology advanced malignancy (T2 and more), patients with hereditary syndromes and those undergoing pancreatoduodenectomy were excluded.
Transduodenal ampullectomy is an effective surgical exploration procedure for unexplained dilation of the cholangiopancreatic duct.
Eur J Med Res
November 2024
Department of Hepatobiliary and Pancreatic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 600 S. Yishan Road, Shanghai, 200233, China.
Article Synopsis
- The study investigates the challenges in diagnosing and treating unexplained dilation of the cholangiopancreatic duct (UDCD) and assesses the effectiveness of transduodenal ampullectomy (TDA) as a potential solution.
- A retrospective analysis of 203 patients (14 from the hospital and 189 from other studies) showed that TDA enhances the diagnostic capability compared to traditional methods, with a significantly higher rate of identifying issues during surgery (78.41% vs. 65.94%).
- The study concludes that TDA is a safe and effective option for diagnosing and treating UDCD, with varying survival rates based on the pathology found, and reports a complication rate of 27.07% but
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